3种口服降糖药物治疗2型糖尿病的成本-效果分析.pdfVIP

申国初级卫室保健 2016 :t在 6 月第 30 卷第 6 期(总第 366 期) 3 种口服降糖药物治疗 2 型糖尿病的成本-效果分析* 赵辉① 摘 要 目的 通过对 3 种口服降糖药物治疗 2 型糖尿病的药物经济学分析，选择成本一效果比最小的用药方案。方法 将 177 例 2 型糖尿病患者随机分为格列美腺组、格列齐特纽和格列，比嗓纽各 59 例，连续用药 1 个月后对 3 纽患者的血糖水平和成 本-效果比进行分析。结果 3 纽总有效率分别为 74.58 1岛、 88.14% 和 77.97 1岛，格列齐特纽总有效率显著高于其他 2 纽 (P 0.05); 3 组成本-效果比分别为 0.78 、 0.27 和 0.35 ，格列关脉组、格列，比嗓组相对于格列齐特纽的增量成本-效果分别 为 -2.53 、 -0.35 。结论 3 种口服降糖药中格列齐特是治疗 2 型糖尿病较为经济、有效的药物。 关键词 2 型糖尿病;口服降糖药;成本;效果 doi:l0.3969/j.issn.l00I-568X.2016.06.0003 [中圄分类号] R587.1 [文献标识码] B [文章编号] 1 ∞ 1-568X(2016)06-仪附7-02 The Cost-etTectivenωs Analysis of Three Kinds of Oral Hypoglycemic Drugs Treatment of Type 2 Diabetes MellituslZHAO HuillChinese Primary Health Care, 2016, 30(6): 7-8 Abstract OBjECTIVE To finish the phannacoeconomics evaluation on three kinds of oral hypoglycemic drugs treatment for type 2 dia? betes mellitus, with reasonably selecting high titer oral hypoglycemic agents to control blood glucose level. METHODS 177 patients with three kinds of oral hypoglycemic drugs treatment of type 2 diabetes mellitus were divided into glimepiride group, gliclazide group and glipizide group(59). After 1 month treatment, blood glucose level and cost-effectiveness were analyzed. RESULTS The total effec? tive rates of three groups were respectively 74.58 1毛， 88.14% and 77.97%. The total effective rate of gliclazide group was higher than other groups(P0.05). The cost-effect were respectively of three group was respectively 0.78, 0.27 and 0.35. The increment cost-ef? fect of glimepiride group and glipizide group were respectively -2.53 and -0.35. CONCLUSION The gliclazide wa