Mattel thinking intrahepatic cholestasis of pregnancy treatment efficacy.doc

 PAGE \* MERGEFORMAT 6 Mattel thinking intrahepatic cholestasis of pregnancy treatment efficacy [Abstract] Objective think Mattel intrahepatic cholestasis of pregnancy treatment efficacy. Method from January 2006 to December 2008 in our hospital during pregnancy liver sedimentation tank Khan a total of 108 patients were randomly divided into two group, respectively, two different approaches to treatment, to form a controlled study. Results The total effective rate was 91.07%, 71.15% in control group, both groups there were significant differences in efficacy (P lt;0.05). Conclusion think Mattel is the treatment of pregnancy Khan sedimentation tank of liver disease is safe and effective drugs. [Keywords:] think Mattel, ursodeoxycholic acid during pregnancy; intrahepatic cholestasis integrated Intrahepatic cholestasis of pregnancy is a pregnancy-specific complications, clinical manifestations of systemic pruritus, dark urine, jaundice, elevated liver enzymes and serum bile acid level rise, even more serious is the impact on the fetus, can lead to premature delivery, fetal distress and stillbirth, the perinatal morbidity and mortality of children increased. At present the drug treatment has been clearly bears deoxycholic acid and dexamethasone. Since January 2006, we think the use of Mattel treatment, a more good clinical efficacy, are reported below. 1 Materials and Methods 1.1 General Information Selected 108 cases of pregnancy are our hospital patients with liver liner deposition Khan, were randomly divided into two groups. The control group 56 cases, the treatment group 52 cases. Gestation two groups of patients, average age, symptoms, liver function and Determination of serum bile acid and other indicators of comparison, the difference was not significant (Pgt; 0.05), comparable. 1.2 Diagnostic criteria (1 Clinical manifestations: no previous history of hepatobiliary disease, third trimester of pregnancy appear pruritus, jaundice and d