Metabolic syndrome and neural mechanisms of cognitive impairment Progress.docVIP

 PAGE \* MERGEFORMAT 16 Metabolic syndrome and neural mechanisms of cognitive impairment Progress [Keywords:] Metabolic syndrome; Cognitive Function Cognitive function is an important human brain functions of the higher cortex, is important to have awareness of the human spirit of one of the activities. In today’s information age, a slight decrease in cognitive function of individuals will have serious implications for psychological and social function, because even mild cognitive impairment will interfere with their work, learning efficiency, quality of life. and hypothyroidism in the absence of significant motor or sensory neurologic symptoms had been caused before the serious cognitive problems. metabolic syndrome (MS), to central obesity, diabetes or impaired glucose regulation, hypertension, dyslipidemia and insulin resistance (IR) is a common pathophysiological basis of their cognitive functions have a broad negative impact, but at what stage, the performance of why the cognitive anomalies, yet have a clear conclusion, and in the clinical treatment of cognitive impairment on rehabilitation assessment has not been given due attention. This article reviews relevant literature to provide a new perspective of cognitive impairment in MS pathogenesis, clinical Diagnosis and treatment of new ideas. 1 Obesity and Cognitive Impairment 1.1 and obesity-related cognitive impairment characteristic of obesity not only increases the risk of other diseases, and the decline of cognitive function also have some impact. Whitmer, etc. (1) for a 1 000 participants of 27 years Investigation that even in the prevention of diabetes and cardiovascular disease at the same time, obesity still increases the risk of dementia, compared with normal weight, obese body mass index (BMI)gt; 30 increased risk of dementia 74%, BMI 25 ~ 30, the risk of dementia increased by 35%. 1.2 and obesity-related cognitive impairment of neural mechanisms of central obesity, as excessive v