Mistletoe pharmacological research.docVIP

 PAGE \* MERGEFORMAT 11 Mistletoe pharmacological research [Keywords:] of Mistletoe [Viscum coloratum (Kom.) Nakai] are distributed in most provinces of China, is a commonly used traditional Chinese medicine. Traditional medicine of mistletoe as a rheumatism drug, its bitter, flat, the liver, kidney, clinical on for rheumatism, blood pressure, miscarriage, etc. [1]; abroad, for the treatment of cancer. In recent years, research and development of faster mistletoe, mistletoe this article on chemical constituents and pharmacological effects were reviewed. An anti-tumor effect Anti-tumor effect of mistletoe was identified as the active ingredients of plant lectin, mistletoe toxic peptides, polysaccharides, alkaloids, polyphenols and flavonoids. Hollow fiber, etc. [2], alkaloids extracted from the mistletoe, animal entity , ascites tumor growth and lung metastasis of mouse Lewis lung cancer were studied, results showed that the mistletoe alkaloids by 50,70 mg / kg to the animals injected on the Lewis lung carcinoma, Ehrlich ascites carcinoma (EAC, sarcoma, S37, Sarcoma S180, reticulocyte sarcoma ascites (ARS and L1210 leukemia were significantly inhibited, and less inhibited C57BL / 6 mice with Lewis lung cancer lung metastases. When the dosage to 90mg/kg, 120mg/kg, the entity ascites tumor and tumor are inhibited, could significantly prolong the life span of mice with multiple tumors [3]. Mistletoe alkali also esophageal cancer, gastric cancer, breast cancer, liver cancer cells significantly inhibited the growth of [4-7 ]. Mistletoe alkali in the 60 ~ 120mg/kg dose of life extension in mice transplanted gastric cancer rate of 33.6% ~ 71.9%; Mistletoe alkali in 0.03125 ~ 0.125mg/mL dose of esophageal cancer cell growth inhibition rate of 39.8% ~ 67.0%, breast cancer cell growth inhibition was 42.7% ~ 70.2%. Mistletoe alkali 120mg/kg dose in the mouse hepatoma H22 on the inhibition rate 73.8%. 2 on the cardiovascular system 2.1 antihypertensive eff