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Ning on the clock reference to sugar on the immune system of diabetic rats_0
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Ning on the clock reference to sugar on the immune system of diabetic rats
[Abstract] Objective To observe the parameters in diabetic rats Tang Mai Ning T lymphocytes and their cytokines in peripheral blood and the immune organ. Methods of 48 male SD rats were randomly divided into diabetic group (DM), diabetes A aspirin treatment group (AD group), diabetes participating in the intervention group Tang Mai Ning (SD group), the control group (NC group). flow cytometry CD3 +, CD4 +, CD8 + T cell count, double-antibody enzyme-linked immunosorbent assay clamp method (ELISA) determination of each group of tumor necrosis factor - @ (TNF-@) and interleukin -6 (IL-6), measured and calculated immune organ. Results DM group CD3 +, CD4 +, CD8 + T cells and thymus index was significantly lower than the NC group (P lt;0.01), while IL-6 and TNF-@ was significantly higher than that of NC group (P lt;0.01), SD group and the AD group, CD3 +, CD4 +, CD8 + T cells and thymus index were significantly higher in the DM group (P lt;0.05), TNF-@ and IL-6 was significantly lower than the DM group (P lt;0.01), compared with the AD group, SD group, these indicators have significantly improved (P lt;0.05). Conclusion ginseng glucose pulse Ning on the immune system of diabetic rats has a protective effect.
[Keywords:] diabetes, aspirin, sugar and pulse parameters to Ning, tumor necrosis factor - @, interleukin -6, rat
Keywords:: diabetes, aspirin, Shendi Tangmaining, TNF-@, IL-6, rat
Type 1 diabetes is on the basis of certain genetic factors, environmental factors as the stimulation of T lymphocytes are involved in pancreatic β-mediated cell damage caused by insufficient insulin secretion in chronic autoimmune diseases [1]. The occurrence and development of diabetes, T-cell subsets and their cytokines play an important role, but also diabetes, T cell subsets and its impact of cytokine function. In this study, ginseng Tang Mai Ning treatment of diabetic r
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