On maternal and cord blood visfatin levels and the relationship between intrauterine growth and development.docVIP

 PAGE \* MERGEFORMAT 13 On maternal and cord blood visfatin levels and the relationship between intrauterine growth and development Of: New Tang Qingling Zhang Li Shang Wu Nan Fang Jing Ping Wang Shuhe [Abstract] Objective To determine the maternal and cord blood visfatin (visfatin) level of Visfatin and the relationship between fetal growth and development. Methods double antibody sandwich enzyme-linked immunosorbent assay method (ELISA) determination of 14 cases of child labor great , 14 cases of intrauterine growth retardation (IUGR) and 14 normal birth weight children of pregnant women and their newborns cord blood serum Visfatin levels of Visfatin and fetal growth and development of the relationship between the level of maternal blood in the Visfatin Visfatin and cord blood levels of correlation. Results (1) IUGR group Visfatin concentration in maternal plasma (41.39 + -5.51) μg / L, significantly higher (34.68 + -4.88) μg / L and a huge group of children (37.34 + -4.40) μg / L, the difference was statistically significant (P lt;0.01, P lt;0.05); large group of children higher than maternal blood concentrations of Visfatin, but the difference was not statistically significant (Pgt; 0.05) . (2) IUGR group Visfatin concentration in cord blood (58.08 + -7.59) μg / L, control group (42.59 + -7.83) μg / L and a huge children group (48.48 + -9.06) μg / L, difference statistically significant (P lt;0.01, P lt;0.05); great group of children Visfatin concentration in cord blood of higher, but the difference was not statistically significant (Pgt; 0.05). (3) higher concentrations in cord blood Visfatin concentration in maternal blood, and was a significant positive correlation between (r = 0.720, P lt;0.001). Conclusion Visfatin concentration increased maternal blood may be related to the pathogenesis of IUGR, maternal blood and cord blood concentrations of Visfatin concentration-related . Keywords:] visfatin; intrauterine growth retardation; great children