On cytomegalovirus infection and infant pneumonia and the relationship between bronchopulmonary dysplasia.docVIP

 PAGE \* MERGEFORMAT 14 On cytomegalovirus infection and infant pneumonia and the relationship between bronchopulmonary dysplasia [Abstract] Objective: To investigate human cytomegalovirus infection and infant pneumonia, bronchopulmonary dysplasia. Methods: Using enzyme-linked immunosorbent assay (ELISA), immunohistochemistry, quantitative PCR technology to clinical diagnostic criteria for infants 66 cases of pneumonia, bronchopulmonary dysplasia 10 cases in children, blood, urine, throat swab secretions and their mothers blood, urine and milk were detected, while detection of 33 healthy children and their mothers. Results: The blood of CMV IgM positive rate of 60.6% of infants with pneumonia group, 48.5% of their mothers, bronchopulmonary dysplasia 60%, 40% of their mothers. 15% positive rate of the control group, the mother of 6%. HCMV antigen positive rate in children with urinary group 71.2% of infants with pneumonia, the 74.2% of mothers milk, bronchopulmonary dysplasia 70%, 70% of their mothers milk, the positive rate of 18% of the control group, 21% of their mothers milk. fluorescence quantitative PCR detection of CMV DNA blood of infants with pneumonia group 57.6% positive rate, positive for CMV DNA in urine rate of 57.6%, pharyngeal secretions CMV  DNA swab positive rate 53%, bronchopulmonary dysplasia group of blood CMV DNA positive rate of 50%, urine CMV DNA60%, 40% of throat swab, blood CMV DNA positive control group rate of 3%, urine CMV DNA6%, pharyngeal swab CMV DNA3%. Conclusion: CMV infection is the infant pneumonia, bronchopulmonary dysplasia, one of the important pathogens, through vertical transmission, so as to facilitate early diagnosis treatment. cytomegalovirus infection and infant pneumonia and bronchopulmonary dysplasia has a direct correlation between [Keywords:] cytomegalovirus infection; infant pneumonia; bronchopulmonary dysplasia CMV infection is caused by the human cytomegalovirus disease in humans. Adult infection ofte