On the biological characteristics of fibroblasts and osteogenic role of the Seminar.docVIP

 PAGE \* MERGEFORMAT 22 On the biological characteristics of fibroblasts and osteogenic role of the Seminar Abstract: The bone defect (particularly large bone defects) of treatment, by the local injury repair complex and the lack of an ideal material, has been plagued clinicians and basic medical workers, a major problem, but as far as possible reached or approached to find a effect of autologous bone graft ideal bone substitute material is even more eager to explore numerous scholars, sought-after goal. Become increasingly active in recent years, bone tissue engineering (bone tissue engineering) technology for the study of this subject has brought a new bright spot and hope. Currently animal experiments have been from the periosteum, bone marrow progenitor cells such as bone orientation (determined osteogenic precursor cells, DOPC)-intensive Department osteoblasts isolated and cultured cells in vitro amplification with the vector combination of replantation of bone defects in vivo to obtain bone defect The success of restoration [1]. At the same time, based on the patient easy acceptance, operability, and more simplicity and other aspects of the considerations, researchers began to turn our gaze inducible osteogenic progenitor cells (inducible osteogenic precursor cells, IOPC). Which are widely distributed in the body, a huge amount of superficial area, drawing convenient, easy to train passage, the rapid proliferation of the fibroblasts first become a research focus. Since many current research is still in the experimental stage, this paper focuses on the biological characteristics of fibroblasts and their osteogenic role are reviewed. Keywords: biological characteristics of fibroblasts in osteogenesis A source of fibroblasts and its biological characteristics Fibroblasts (fibroblast) is the most common connective tissue cells from the embryonic mesenchymal cells (mesenchymal cell) differentiation from. In the connective tissue, fibroblasts also in its ma