On the combined treatment of high blood pressure.docVIP

 PAGE \* MERGEFORMAT 10 On the combined treatment of high blood pressure Author: Mary left side of Evergreen Mingyuan Wang Baohai [Paper Keywords:] hypertension; combination therapy [Abstract] This paper discusses the benefits of the treatment of hypertension and its mechanism in detail for the eight kinds of high blood pressure combined treatment programs. Hypertension is the most common cardiovascular disease, is a major public health problem throughout the planet, but also endanger human health dangerous killer. About 120 million hypertension patients in China, and the number is increasing. China’s current there is 1 case per 212 seconds stroke occurs every 21 seconds, 1 died of stroke, end-stage renal disease and heart failure are increasing every year. Generally the largest single drug therapy is the only control 30% of the defects in blood pressure in patients with moderate to severe high blood pressure control effect even worse. A reasonable combination therapy can compensate for lack of a single antihypertensive drug, 2 species or more than two kinds of mechanism of action of various drugs combined, its antihypertensive effect may be superimposed or synergistic. So, a small dose can produce the desired blood pressure lowering effect and reduce adverse reactions. Interim prescribing combination therapy is divided into a joint agents (also known as on-demand joint) and fixed-drug combinations. A fixed proportion of the drug combinations because of the economic convenience, compliance is good, apply to China’s current conditions are conducive to a low level, wide coverage. More in line with the Joint Interim prescribing individualized. A thiazide diuretic and protection of potassium-sparing diuretics in combination This is the same combination of drugs, thiazide diuretics to reduce blood pressure and blood volume reduction, but the long-term application prone to low potassium, low magnesium and other adverse re