Pantoprazole combined with famotidine treatment of duodenal ulcer.docVIP

 PAGE \* MERGEFORMAT 11 Pantoprazole combined with famotidine treatment of duodenal ulcer [Abstract] Objective To observe the oral administration of pantoprazole combined with famotidine treatment of active duodenal ulcer (DU clinical efficacy. Methods of Helicobacter pylori (HP-negative activity of the 59 patients with duodenal ulcer were randomly divided into two groups, which together with the group of 32 patients given pantoprazole combined with famotidine treatment group of 27 patients were given single drug pantoprazole treatment. a course of 4 weeks. The results of treatment, the pain lost time, the combination group was 2.4 + -2.2 days, the single drug group and 3.7 + -2.5 days, two groups had significant difference (P lt;0.05. in the ulcer healing rate, the combination group was 90.6%, single healing rate of 81.5% drug group showed no significant difference (Pgt; 0. 05. Conclusion of oral pantoprazole therapy combined with famotidine DU, relieve symptoms quickly and effectively, to a certain extent, improve the rate of ulcer healing , and worth further clinical application. [Keywords:] pantoprazole peptic ulcer famotidine Duodenal ulcer (duodenal uncler, DU is the digestive system of the common disease, accounting for about 80% of the peptic ulcer. Research has made it clear, DU occurrence with a variety of factors, including gastric acid, gastric Helicobacter pylori protease and factors such as increased attack, and the gastric mucosal barrier, mucosal blood flow, prostaglandins, bicarbonate secretion and epithelial regeneration of the weakened defense factor. Although the initiating factors may vary, but in the formation of ulcers process, the acid digestion itself always occupy a decisive factor, therefore, inhibition of gastric acid into DU treatment of one of the most important measures [1]. current proton pump inhibitor (PPI or H2 receptor antagonist (H2RA and other acid-suppressing DU treatment agent is the most commonly used convention