Progress in cancer stem cell research.docVIP

 PAGE \* MERGEFORMAT 9 Progress in cancer stem cell research [Abstract] exists in tumor cancer stem cells. Very small number of cancer stem cells, but ignored the tumor, metastasis play a decisive role. Cancer stem cells are a special type of stem cells, possess a high degree of proliferative capacity and self-renewal capability and can be multiple, including tumor cells to differentiate into a variety of cells, including daughter cells, the result is to maintain stability in the number of cancer stem cells and produce tumors. This article describes the history of cancer stem cells, characteristics as well as the relationship between adult stem cells, cancer stem cell theory Finally, the clinical significance of the tumor had a preliminary elaboration. [Keywords:] stem cells; TSC; cancer stem cells; tumor Stem cells are found in animals and humans is a special function of cells with multiple differentiation capacity and self-renewal capacity. Stem cell biology features include: (1) or all-round versatility, stem cells have the potential to be divided into many types of cells; (2) self-renewal capacity of stem cells, once formed, the body has a life of self-renewal capacity, through the inequality a split the self-renewal and produce differentiated progenitor cells, maintaining the stability of the body’s tissues and organs. (3) a high degree of proliferative capacity, for the maintenance of normal function of the body plays an important role [1]. Cancer stem cells (tumor stem cells, TSC) expressed as a special type of stem cells, possess a high degree of proliferative capacity and self-renewal capacity, but also have multi-differentiation potential. TSC proliferation process, through an uneven split, a TSC split to form a new TSC and another could eventually include the tumor cells to differentiate into a variety of cells, including daughter cells, the result is to maintain stability and produce the number of TSC tumors. 1 TSC origin 1.1 The defini