Progress in brain tumor stem cell research.docVIP

 PAGE \* MERGEFORMAT 29 Progress in brain tumor stem cell research Abstract More and more research shows that only a small part of the tumor tissue cells have unlimited proliferation and self-renewal capability of these cells similar to stem cells is the basis for the development of tumor, that tumor stem cells. Such cells are characterized by self-renewal capacity of out of control. Cancer stem cells has grown from several solid tumors were separated, the recent glial cell tumors and small cerebellar medulloblastoma research has confirmed that it contains the above-mentioned stem cell-like tumor cells. In this paper, in recent years, brain tumor stem cells, on the proposal of the concept, identification, sources, and neural stem cells in brain tumor treatment differences and inspiration to discussions with a view to the occurrence of brain tumors, and therapy. 【Key Words】 cancer stem cells As the nervous system of common diseases, human high-grade gliomas are extremely invasive capacity of malignant cells under the microscope show its much more than enhanced by the contrast agent imaging borders, even beyond the borders of the tumor found at 7cm. Such biological characteristics make the brain function of advanced imaging technology is difficult to achieve the desired sensitivity and specificity, but as a means of supporting minimally invasive neurosurgery techniques and three-dimensional conformal radiotherapy techniques and therefore lose their places in the treatment of other diseases good effect. Recent results showed that, after a combined treatment of anaplastic astrocytoma and glioblastoma multiforme tumor the median survival time of only 18 months and 12 months. To improve efficacy, it is their biological characteristics of in-depth studies in 2003, Sing [1] from the brain tumor tissues isolated from brain tumor stem cells (brain tumor stem cell, BTSC), this new research perspective is bound to plastic treatment of stromal tumors