Progress in the pharmacological activity of Sophora flavescens.docVIP

 PAGE \* MERGEFORMAT 17 Progress in the pharmacological activity of Sophora flavescens Author: Xu Jin-Ning Zhang Heming Zhao Xiuhua [Keywords:] Sophora Sophora (Sophoraflavescens Ait) as Sophora species, is a long history of traditional medicines in China, one of their sexual taste the bitter cold, in the final heart, liver, kidney, colon, bladder through, with heat dampness, expelling wind insecticide, diuretic functions. For hot dysentery, hematochezia, jaundice, urine retention, Chibai bands, Yin itching, eczema, wet sores, skin itching, scabies, leprosy, foreign rule trichomonas vaginitis. The main ingredients of matrine matrine, oxymatrine oxymatrine and other alkaloids, matrine and alcohol kurarinol, Sophora butanol kuraridinol and other flavonoids, and the other containing amino acids, volatile oils, sugar, organic acids, which esters ingredients [1]. In recent years, right Sophora chemical composition and biological activity of the deepening at home and abroad right now Sophora Research pharmacological activity are summarized below. An anti-tumor activity Tumor occurrence and development of not only tumor cell proliferation and differentiation of abnormalities caused by abnormal apoptosis of tumor cells but also results. Therefore, the inhibition of tumor cell proliferation and induce tumor cell differentiation and apoptosis, clinical treatment of cancer have a certain significance. In recent years, studies have shown that matrine malignant hydatidiform mole, choriocarcinoma, uterine cancer, Ai Shi ascites cancer cells within the tumor and lymph varying degrees of suppression and eradication of the role of matrine on tumor cells have a selective killing effect , but also by changing the cellular nucleic acid molecule sequence, inhibit tumor growth, and this effect is a broad, multi-parts [2]. The result showed that matrine treatment of advanced cancer, can reduce symptoms and prolong survival time, without disrupting the normal production of white