Proton magnetic resonance spectroscopy in brain tumors Application Progress.docVIP

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2017-05-05 发布于浙江
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Proton magnetic resonance spectroscopy in brain tumors Application Progress.doc

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Proton magnetic resonance spectroscopy in brain tumors Application Progress

Proton magnetic resonance spectroscopy in brain tumors Application Progress [Abstract] correct diagnosis of brain tumors and to better its treatment and treatment. 1H MRS is to obtain information on non-invasive tumor biochemical technology, the traditional imaging technology provides an important supplement. For non-neoplastic lesions and difficult surgery that require radiation or chemotherapy tumor lesions, non-invasive and accurate method to determine the nature of lesions can replace unnecessary biopsies. In this paper, 1H MRS in brain tumor classification and grading of the application, observe the tumor response and tumor progression of treatment is to decide the important cancer treatment program of molecular imaging techniques. [Keywords:] 1H MRS; brain tumor; Diagnosis Proton magnetic resonance spectroscopy (proton magnetic resonance spectroscopy, 1H MRS) is to obtain biochemical information on the organization and gradually applied to the brain lesion classification of non-invasive methods. The first MRS study of brain tumor and normal tissue, there is significant difference between the 1H spectra [1]. Recent studies have shown that the metabolism of brain tumors, and imaging characteristics without a clear relationship [2]. Commonly used Gd-DTPA enhanced show the nature and extent of the lesions, but enhanced outside the 1H MRS can show abnormalities, suggesting that application of molecular imaging methods could be improved 1H MRS brain tumor tissue to identify and apply the decision radiotherapy, stereotactic biopsy tumor location as well as the scope of surgical resection [2]. In recent years, 1H MRS has been increasingly used in clinical and research. Purpose of this paper is a summary of the current application of 1H MRS: (1) diagnosis of lesions; (2) tumor grade; (3) observation of the treatment response and tumor progression; (4) facilitate the development of treatment programs; (5) to determine the prognosis. 1H MRS of the significance