Prunella vulgaris in the study of flavonoid compounds.docVIP

 PAGE \* MERGEFORMAT 9 Prunella vulgaris in the study of flavonoid compounds Author: Wang Ju Tang Chu Li-ying Fu Meihong He Yan Fang Jing [Abstract] Objective To study the efficacy Prunella ingredients. Methods such as silica gel column chromatography for separation and purification of Prunella vulgaris, according to spectral data analysis and chemical structure of compounds were identified. Results Isolation and identification of the three compounds were identified on ① quercetin-3-O-β -D-glucoside; ② hesperidin, that is, 5,7,3 ‘- 3-hydroxy -4’ - methoxy - flavanone-7-O-α -L-rhamnopyranosyl - (1-6)-β -D-glucopyranoside; ③ rutin. Conclusion Compounds ② for the first time isolated from Prunella vulgaris. [Keywords:] Prunella vulgaris chemical constituents of flavonoid glycosides Abstract: ObjectiveTo study the constituents in the flower of Prunella vulgaris L.. MethodsThe herb was extracted and purified with the column chromatography on silica gel and Sephadex LH  20, identified by the spectrum analysis and chemical method.Results3 compounds were isolated from the plant , and their structures were elucidated as ① quercetin-3-O-β -D-glucoside, ② hesperidin and ③ rutin.ConclusionCompound ② was isolated for the first time from Prunella vulgaris L. Keywords:: Prunella vulgaris L.; Flavonoids; Constituents To Labiatae Prunella vulgaris Prunella vulgaris Prunella vulgaris L. Plant dry flowers is to blindly used traditional Chinese medicine before they are set out in ‘Shen Nong Ben Cao Jing’, has a medicinal for thousands of years of history. Of traditional medicine that has a clear fire, eyesight, Sanjie, swelling of the effect, for the Mu Chi swelling, pain, headache, dizziness, M. scrofulaceum gall tumors, breast swelling and pain and other symptoms. Modern research shows that it has a step-down, anti-bacterial, anti-virus, anti-inflammatory, anti tumor and hypoglycemic variety of pharmacological effects in clinical practice for the treatment of tube