Pseudomonas aeruginosa producing inducible β -lactamase detection and its impact on 20 kinds of antibiotics Analysis.docVIP

Pseudomonas aeruginosa producing inducible β -lactamase detection and its impact on 20 kinds of antibiotics Analysis [Abstract] Objective To understand the clinical isolates of Pseudomonas aeruginosa in Foshan producing inducible β -lactamase and its drug resistance. Methods used by the U.S. DADE middle Micro Scan Auto Scan-4 analyzer and its NC21 microbial identification and susceptibility panels and in accordance with NCCLS standards Ver Sion 22 analysis software, for detection of Pseudomonas aeruginosa producing 128 inducible β -lactamase and the sensitivity to 20 antibiotics. Results (1) of Pseudomonas aeruginosa to ceftazidime, piperacillin / tazobactam, ciprofloxacin, amikacin, cefepime, imipenem sensitivity as high as between 57.0% ~ 80.0% . Tobramycin, piperacillin, gentamicin second, the lower the sensitivity of other cephalosporins. (2) 128 Pseudomonas aeruginosa producing inducible β -lactamase were 115 (89.8%) in producing inducible β -lactamase strains, piperacillin / tazobactam, ceftazidime, piperacillin , An Song Nam-induced Pseudomonas aeruginosa producing inducible β -lactamase of the occurrence rate was 53.9% ~ 80.0%. (3) producing inducible β -lactamase strains to piperacillin / tazobactam, amikacin, cefepime, ceftazidime, ciprofloxacin, tobramycin and other antibiotics, the sensitivity was significantly higher than non - producing inducible β -lactamase strains, and ampicillin / sulbactam, sulfamethoxazole sensitivity is completely the opposite (P amp;lt;0.05). Conclusion Foshan antibiotic producing Pseudomonas aeruginosa-induced inducible β -lactamase rates are relatively high, piperacillin / tazobactam, ceftazidime, piperacillin, An Song Nam is a strong inducer for enzyme production strain can choose ciprofloxacin, amikacin or joint use of antibiotic-resistant enzyme. [Keywords:] Pseudomonas aeruginosa; inducible β -lactamase; antibiotics; resistance [Abstract] Objective To investigate the pseudomonas aeruginosa isolated from Qingyuan hospi