Radish Seed alkaloids on the Apo E knockout mice Serum Lipid.docVIP

 PAGE \* MERGEFORMAT 6 Radish Seed alkaloids on the Apo E knockout mice Serum Lipid [Keywords:] Radish water-soluble alkaloids, Apo E knockout mice, blood lipids Radish seeds with lower gas phlegm, digestion addition to inflation of power. Danxi Zhu praised Radish “Phlegm has the power to push the wall down the wall.” Radish seeds are water-soluble alkaloids sinapine (Sinapine) as the main ingredient, widespread cruciferous plants in a quaternary ammonium material. hyperlipidemia medicine causes more be classified as “phlegm” “Blood”, the professor of this research is based on cover Guozhong causes combined hyperlipidemia pathogenesis and the efficacy of radish seed characteristics and the clinical experience, by observing the water-soluble alkaloids of radish seed Apo E knockout mice blood lipids to investigate the role of radish seed lipid-lowering soluble alkaloids. 1 Materials and methods 1.1 Materials Radish Seed water-soluble alkaloids from the Jilin Academy of Traditional Chinese Medicine preparation of new drug center. Beijing Vital River offers male Apo E knockout mice 75, 13 weeks of age, body weight (22 +-2g, clean. Electronic record weight scale AWH (SI 2.5 kg, BD / BC 518-20 refrigerator, 4 refrigerator, Q/IFGM018 2000 low speed centrifuge, HH W21 600 electric thermostat water bath and small desktop centrifuge (Shanghai Medical Instruments Factory, PERLONG, pus 2018 semi-automatic biochemical analyzer (Beijing New Technology Co., Ltd. Prong. basal diet: 26.0% corn meal, flour 29.0%, 28.0% soybean meal, dicalcium phosphate 1.4%, powder 1.6%, 5.0% fish meal, bone meal 5.0%, salt 1.0%, 1.5% vitamins, trace elements 1.5%. Feigan feed: from 10.0% lard, 2.0% cholesterol, 20.0% sucrose, 5.0% egg yolk powder, 0.2% bile, 0.2 % methyl thiouracil, 62.6% based on feed preparation. 1.2 Methods 1.2.1 Grouping and administration The Apo E knockout mice (high fat diet were randomly divided into 5 groups, n = 15. Radish soluble alkaloids