Report of 12 cases of allergic reaction to azithromycin.doc

 PAGE \* MERGEFORMAT 7 Report of 12 cases of allergic reaction to azithromycin [Keywords:] azithromycin allergic reactions Azithromycin treatment of children with mycoplasma pneumonia and community-acquired pneumonia, results were satisfactory, the current application is becoming more widespread. Past more attention to their response to liver damage and gastrointestinal side effects, but in recent years, allergic reactions (including anaphylactic shock) can occur, in order to pay attention, now three years, our department occurred in 12 cases of allergic reactions reported as follows. 1 Data 1.1 anaphylactic shock A total of three cases, of which 2 males and 1 female; age of 10 years, 6 years old, 1 year and 1 cases; two cases of mycoplasma pneumonia, bronchial pneumonia in 1 case. Both penicillin and cephalosporins history of drug allergy. To give in 1 case. Children, male, 6 years old, due to fever 6 ~ 7 d, with irritating dry cough, after serving traditional Chinese medicine, erythromycin and other bad treatment come to my hospital treatment. Palpation: T 39 ℃ , heart rate fast, coarse breath sounds lungs, no rales, chest X-ray showed pneumonia in the lower left. MP IgM 1:1 280, CRP 46 mg / L. Mycoplasma pneumonia to be patient, I azithromycin (express Rocand, Jiangsu Chi Chuan Pharmaceutical Co., Ltd., batch number 06,032,301) intravenous drip treatment. 10 min when the infusion, the children v. chest, pale, cold sweats, nausea, abdominal pain, followed by facial see scattered maculopapular rash, and rapid increase in cold extremities, skin patterns, heart rate fast and weak, the mouth weeks micro cyanosis, etc. blood pressure 60/50 mm Hg. Stop using azithromycin, oxygen, intravenous injection of epinephrine, dexamethasone, and promethazine, etc., about 10 min later, to alleviate the above-mentioned symptoms and signs, looking to red, chest tightness disappears. After hospitalization. Follow-up history, there have been penicillin, cephalosporins and ot