Report of 17 cases of orthotopic heart transplantation.doc

 PAGE \* MERGEFORMAT 15 Report of 17 cases of orthotopic heart transplantation Study: Liu days, the Ma Yanping, Wang, Wang Minghua, Liu Lu Qi, Li PJ, Li, Xu Li, Min [Abstract] Objective To investigate the effect of heart transplantation the main factor. Methods March 2003 to July 2009 were operated continuously for 17 cases of orthotopic heart transplantation, of which 13 cases of dilated cardiomyopathy, hypertrophic cardiomyopathy 3 cases of ischemic cardiomyopathy in 1. using standard orthotopic heart transplantation in 1 case, venous anastomosis in situ dual-chamber heart transplantation in 16 cases, 1 case of kidney transplantation .5 cases combined preoperative moderate pulmonary hypertension, NO inhalation and other measures to reduce pulmonary arterial pressure, 2 patients with severe pulmonary hypertension by increasing prostacyclin treatment. anti-rejection therapy with cyclosporine A (CsA) + corticosteroid (Pred) + mycophenolate mofetil (MMF) Joint programs. Results in 2 cases there were early postoperative acute rejection, high dose methylprednisolone pulse therapy for 3 days remission, 1 patient on day 3, renal failure, given hemodialysis treatment, 1 patient died of enterovirus 25 h tract, heart and kidney transplantation in 1 patient who died at 18 days after pulmonary embolism. followed up 1 to 76 months, late death in 1 case, 1 case died of kidney failure at 35 days after surgery and neurological toxicity of anti-rejection drugs survived heart function to the case 0 ~ level, to resume normal work and life, late acute rejection occurred in 1 case, the steroid pulse therapy returned to normal. Conclusions Heart transplantation is an effective treatment method for end-stage heart disease, strict control of receptor indications, good for the heart protection, the appropriate surgical technique and strict perioperative management of patients with heart transplantation can improve the results. reversibility of severe pulmonary hypertension, lun