Risperidone in the treatment of citalopram combined effect of obsessive-compulsive disorder.doc

 PAGE \* MERGEFORMAT 6 Risperidone in the treatment of citalopram combined effect of obsessive-compulsive disorder [Abstract] Objective To investigate the combination of citalopram of risperidone treatment of obsessive-compulsive disorder patients. Methods 40 patients with OCD were randomly divided into combined risperidone and citalopram groups, treatment 8 w, with obsessive-compulsive disorder Scale (Y- BOCS, Hamilton Anxiety Scale (HAMA, Hamilton Depression Rating Scale (HAMD evaluated. Results After treatment, two Y-BOCS, HAMA, HAMD scores were significantly lower, but also to merge Risperidone significantly. Conclusion Risperidone citalopram in the treatment combination can enhance the efficacy of obsessive-compulsive disorder. [Keywords:] risperidone in obsessive-compulsive disorder Citalopram Difficult to treat obsessive-compulsive disorder, single-drug results are poor, combined with risperidone can increase the efficacy of citalopram in the treatment, these are as follows 1 objects and methods 1.1 Object Are in line with the Chinese Classification and Diagnostic Criteria of Mental Disorders 3rd Edition diagnostic criteria for obsessive-compulsive disorder, obsessive-compulsive disorder Scale (Y-BOCSgt; 16 points, both for the first time the disease, without treatment, no physical disease. A total of 40 patients were randomly divided into two group, 20 cases of combined risperidone group, 8 males and 12 females, mean age (32.7 + -11.2 years, duration of 4 months to 16 years, the average (3.9 + -5.2 years, 20 patients with citalopram, 10 males and 10 females, mean age (35.2 + -11.2 years, duration of 5 months to 18 years, the average (3.6 + -4.7 years, more than 2 groups the differences were not statistically significant (P allgt; 0.05. 1.2 Methods Combined risperidone group citalopram 20 ~ 40 mg / d, risperidone 0.5 ~ 1 mg / d. citalopram alone in the citalopram group dose 30 ~ 60 mg / d, regimens 8 w . with OCD Scale (Y-BOCS, Ha