Superoxide dismutase status of research.docVIP

 PAGE \* MERGEFORMAT 23 Superoxide dismutase status of research Keywords:: superoxide dismutase; physiological function; properties; Application Abstract: The superoxide dismutase of biological superoxide anion radical in vivo is an important enzyme, has important physiological functions in medicine, food, cosmetics have broad application prospects. Are from the classification, distribution, structure, properties, catalytic mechanism, preparation, application, etc. of the superoxide dismutase progress in basic research. Keywords:: superoxide dismutase; physiological function; properties; Application Advance in current research of superoxide dismutase. Abstract: Superoxide Dismutase (SOD) is an important enzyme in organism, which can remove superoxide free radical.It is wide-ly used in clinical treatment, food, and cosmetic industry for its important physiologic function.This review presents a basic reseach outline of SOD, including classification, distribution, structure, property, the catalyse mechanism, preparation and application. Keywords:: Superoxide dismutase; Physiologic function; Property; Application In 1938, Mann and Keilin [1] for the first time isolated from bovine red blood cells of a blue copper protein (Hemocuprein), 1969 Nian Mccord and Fridovich [2] found that the protein with catalytic O 2, disproportionation reaction functions, Therefore, this enzyme called superoxide dismutase (Superoxide Dismutase, SOD, EC). The enzyme is an important body of oxygen free radical scavenger, able to balance the body’s oxygen free radicals, thus avoiding the concentration of superoxide anion when the body is too high, due to adverse reactions, while SOD is a valuable use of drugs enzymes. Research on SOD extensive attention from scholars at home and abroad, involving chemistry, biology, medicine, daily chemical industry, the areas of food, is a hot research topic. Through years of efforts, basic research in the SOD has made great achievements. A