Syphilis during pregnancy on the timing of PMTCT interventions.docVIP

 PAGE \* MERGEFORMAT 17 Syphilis during pregnancy on the timing of PMTCT interventions Of: Tan Xiaoping Liu Honggui Xiong Haiyan Li, Bi Hua Peng Guiyu Ning Jingchun [Abstract] Objective To study the different stages of syphilis in pregnancy, treatment or therapy Mei drive poor pregnancy outcomes and the incidence of congenital syphilis. Methods 252 cases of syphilis in pregnant women, pregnancy, screening and diagnosis and begin treatment based on the time, divided into 4 groups: 102 patients treated before pregnancy; 77 patients treated during pregnancy, including pregnancy ≤ 20 weeks of treatment, 32 cases of pregnancygt; 20 weeks of treatment group, 45 cases; no treatment group 73 cases. Comparison of adverse pregnancy outcomes between the groups, newborn positive syphilis serology and a clinical presentation of the incidence of neonatal congenital syphilis. The results of different treatment time, the incidence of adverse pregnancy outcomes, the treatment group before pregnancy was 17.6% (18/102), pregnancy treatment group 32.5% (27/77), no treatment group 56.2% (41/73), comparison between groups was incremental, the difference was statistically significant (P lt;0.01); different clinical manifestations incidence of adverse pregnancy outcomes, the incubation period syphilis 24.9% (43/173), a syphilis, 44.1% (15/34), secondary syphilis, 57.7% (26/45), 3 group, the difference was statistically significant (P lt;0.01); different intervention time congenital Comparison of the incidence of syphilis, the treatment group before pregnancy and pregnancy ≤ 20 weeks of treatment, no significant difference between groups (Pgt; 0.05), pre-pregnancy group toluidine red umbilical cord blood and neonatal clinical test positive rate incidence rate of congenital syphilis lower than the pregnancygt; 20 weeks of treatment group, and pregnancygt; 20 weeks of treatment group was significantly lower than the untreated group, the difference was statistically significant (P