The field of liver transplantation in China should pay attention to basic research clinical.docVIP

 PAGE \* MERGEFORMAT 21 The field of liver transplantation in China should pay attention to basic research clinical [Abstract] With the newer immunosuppressive agents have been brought forth, surgery and an overall improvement in monitoring techniques, liver transplantation for end-stage liver disease as conventional and effective methods. The development of clinical features of liver transplantation were: hepatitis B related end-stage liver disease is the most important indication of progress over the standard of Milan HCC share the majority of cases of liver transplantation, donor source of uncertainty. In view of this, the author of liver transplantation should be made to effectively combat hepatitis B hepatitis C virus re-infection, effective control of tumor recurrence after liver transplantation liver, use of marginal donor organ function and protection of liver transplantation immunology, infectious diseases combined specific aspects of liver transplantation should be more focus on clinical basic research. [Keywords:] liver transplantation, immunosuppressive agents, donor, immune tolerance ABSTRACT: Liver transplantation has become an effective and routine treatment for end stage liver diseases with the employing of new immunosuppressants and surgical techniques. The characteristics of our country s liver transplantation are as follows: the indication for liver transplantation consists mainly of HBV related end stage liver diseases, patients with liver cancer beyond Milan criteria account for a high rate, and donor origin is not definite. The author thinks that liver transplantation in our country should emphasize basic clinical research, such as prevention of HBV reinfection and tumor relapse after liver transplantation, employing of marginal donor, organ function protection, immunology of liver transplantation, and specific infection around liver transplantation. KEY WORDS: liver transplantation; immunosuppressant; donor; immunological tol