Toxicity of and countermeasures Tripterygium.docVIP

 PAGE \* MERGEFORMAT 23 Toxicity of and countermeasures Tripterygium Of: Wangyue Min, Zhang Shiliang, Xia Suxia, Tangsi [Abstract] Objective: The side effects of triptolide and its influencing factors, including toxicity and poisoning the major performance factors of toxicity, the machine of toxic management, ways to reduce the toxicity, poisoning and other solutions are reviewed. [Keywords:] Hook, toxicity Tripterygium (Tripterygium wilfordii) of temperature, taste bitter. Has Qufengchushi getting a vivid, swelling and pain, killing and detoxification. Modern research found to have anti-inflammatory, immunosuppressive, anti-growth anti-tumor, antibacterial, analgesic and other activities. In recent years, found that triptolide rejection in organ transplantation, autoimmune disease, nephrotic syndrome, cancer and so a significant effect in clinical practice for rheumatoid arthritis, rheumatoid arthritis, bruises, renal ball nephritis, lupus erythematosus, nephrotic syndrome and other treatment of difficult diseases. So far, domestic and foreign scholars from Tripterygium genus about 70 compounds were isolated, mainly alkaloids, diterpenoids (eg, triptolide that triptolide), triterpenes, sesquiterpene class and polysaccharides [1]. Tripterygium reported occurrence of the last half century herbal poisoning one of the most. With its active ingredients and pharmacological effects related to the deepening of the increase in exploration and clinical application, its side effects and influence factors more attention. This paper studies in recent years about the toxicity of Tripterygium be reviewed. 1 Tripterygium mainly toxicity and poisoning Wilfordii poisoning mainly in cardiac, nervous system, kidney damage based, or even heart and liver hemorrhage or necrosis, the rapid development and high mortality. Symptoms showed progressive increase, has shown signs of nausea, vomiting, abdominal pain, diarrhea was followed by thin veins few and weak,