持续冲洗rh-aFGF合并负压引流对难愈性创面愈合过程的修复效应.pdfVIP

197 河南大学学报(医学版) 2015 年 9 月 第 34 卷第3 期 持续冲洗 rh-aFGF 合并负压引流对难愈性创面愈合过程的修 复效应 王付勇，李华强势 (开封市中心医院整形烧伤外科，河南开封 475000) 摘 要:曲曲曲 探讨持续冲洗重组酸性成纤维细胞生长因子(rh-aFGF) 合并负压引流对难念性创面愈合过程的修 复效应。方 ít 以入院病例号为编号，根据随机数字表，将 80 名难愈性创面患者随机分成 2 纽，每纽 40 例。治疗 过程中，观察纽患者予以 5 支 rh-aFGF 配成冲洗溪，冲洗创面，并合并负压引 3元;对照纽患者给予生理盐水画己成冲 洗液，同观察组冲洗方法进行冲洗。观察创面愈合情况以及深部组织外露面积。幡.. 肉眼观察，观察组患者创 面肉芽组织生长良好，优于对照纽肉芽生长情况;引流 10 d 后，观察组和对照纽创面愈合率分别为(64.2 ::1: 3.2) %和 (27.6 土2.6) %，前者优于后者 (P 0.05); 观察纽和对照组伤腔容积减少值分别为(l6.4 ::1: 2.Z)mL 和 (5.9 ::1: 2.6)mL ，前者优于后者 (P 0.05) 。错俗 Rh-aFGF 持续冲洗创面能够营养创面周围神经，可促进皮肤修复过 程，优化难愈性创面修复效采。 关键词:重组酸性成纤维细胞生长因子;持续冲洗:负压引流;难愈性创面 文章编号: 1672 一7606(2015)03 日 197-03 中图分类号:R594.1 文献标识码:A The effectiveness of rh-aFGF irrigating and negative pressure drainaging for the treatment of labourious wound surface WANG Fuyong , LI Huaqiang 提 (Deþartment 01 Plastic and Burn Surgery , the Central Hos户ital 01 Kaileng , K叫作ng， Henan 475000 , China) Abstract: 0战jective To investigate the recovery effects of recombinant human acid fibroblast growth facto (rh- aFGF) irrigating and negative pressure drainaging for the repairing process of difficult and complicating wound surface. Methods All of 80 cases who with labourious wound surface were divided into two groups by means of random digits table. 40 cases of observing group were treated with rh-aFGF irrigating and negative pressure drainaging , 40 cases of control group were treated with Sodium Chloride rinse solution instead of rh-aFGF , and the wound healing situation and deep part exerted area were observed.Results 10 days later , the wound healing rates of observing group and control group was 64.2 % and 27.6 %, the mean wound cavi