Effects of Varying Doses of Plain Bupivacaine with Fentanyl in Patients Undergoing Cesarean Section Haemodinamics and Neonatal Outcome.docVIP

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Effects of Varying Doses of Plain Bupivacaine with Fentanyl in Patients Undergoing Cesarean Section Haemodinamics and Neonatal Outcome.doc

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Effects of Varying Doses of Plain Bupivacaine with Fentanyl in Patients Undergoing Cesarean Section Haemodinamics and Neonatal Outcome

Clinical Science Macedonian Journal of Medical Sciences. 2009 Dec 15; 2(4):324-329. doi:10.3889/MJMS.1857-5773.2009.0076 Clinical Science OPEN?ACCESS Effects of Varying Doses of Plain Bupivacaine with Fentanyl in Patients Undergoing Cesarean Section: Haemodinamics and Neonatal Outcome Atanas Sivevski Department of Anesthesiology, University Clinic of Gynecology and Obstetrics, Faculty of Madicine, University “Ss Kiril and Metodij”, Skopje, Republic of Macedonia Abstract Aim. The purpose of this study was to evaluate a three different regimes of spinal anaesthesia Key words: for caesarean delivery as well the incidence and severity of maternal hypotension and its influence over neonatal outcome. spinal anaesthesia; cesarean delivery; hypotension; neonatal outcome. Correspondence : Material and Methods. Sixty (60) term healthy (ASA I) parturients scheduled for elective or non-elective caesarean delivery without fetal distress under spinal anaesthesia were randomly divided in three groups: group SA F10 (n = 20) received plain bupivacaine 12 mg plus 10 μg fentanyl, group SA F20 (n = 20) received 11 mg plus 20 μg fentanyl and SA LD group (low dose, n = 20 ) received 8 mg bupivacaine plus 20 μg fentanil. Ephedrine 5-10 mg i.v. bolus was given when systolic blood pressure (SBP) was 95 mmHg. Maternal blood pressures, efedrin dosage, sensory level of anaesthesia, Apgar scores and neonatal umbilical cord blood acid-base (Ua) status were evaluated. Prim d-r Atanas Sivevski, m-r sci University Clinic of Gynecology and Obstetrics,Skopje,RepublicofMacedonia e-mail: asivevski@ Received: 13-Jul-2009 Revised: 15-Nov-2009 Accepted: 20-Nov-2009 Online first: 24-Nov-2009 Results. Spinal block provided surgical anaesthesia in all patients. Peak sensory level was higher in the greatest bupivacaine group (4.9 ± 1.33, 5.0 ±1.21 vs. 5.4 ±1.55). Parturient who received 12 mg bupivacaine (SA F10 group) develop significantly d