Axillary Recurrences after Sentinel Node Surgery—Results over Ten Years in a University Hospital英文文献资料.docVIP

Journal of Cancer Therapy, 2012, 3, 846-852 /10.4236/jct.2012.325108 Published Online October 2012 (http://www.SciRP.org/journal/jct) Axillary Recurrences after Sentinel Node Surgery—Results over Ten Years in a University Hospital Helle Eilertsen , Ellen Schlichting , Marianne Efskind Harr , Daehoon Park , Torill Sauer , 1 2 3 4 1,5 6 1,2* Siri Lar?nningen , Rolf Kaaresen 1 Medical Faculty, University of Oslo, Oslo, Norway; 2 Department of Breast and Endocrine Surgery, Oslo University Hospital, Oslo, Department of Neurosurgery, Oslo University Hospital, Oslo, Norway; Department of Pathology, Vestre Viken Hospital, Department of Pathology, Oslo University Hospital, Oslo, Norway; Cancer Registry of Norway, Oslo, Norway. Norway; Drammen, Norway; Email: 3 4 5 6 * rolf.karesen@medisin.uio.no Received July 10 , 2012; revised August 15 , 2012; accepted August 27 , 2012 th th th ABSTRACT Background: Sentinel node biopsy (SNB) was introduced at Ullevaal University Hospital in 2000. This article presents results from the first ten years use of the method. Material and Methods: A prospective registration of 2762 patients was made from 2000 through 2009. Results: The median follow-up time was 51 months. The overall detection rate was 93%. 36% of the patients with positive SNs had non-sentinel metastases. These were significantly associated with a macrometastatic SN and a primary tumour 20 mm. 18% of patients with sentinel metastasis ≤ 2 mm had non-sentinel metastases. 14 patients with negative SN (0.7%) developed axillary recurrence. 32% with a preoperative diagnosis of ductal carcinoma in