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Basal Cell Carcinoma in Asians A Retrospective Analysis of Ten Patients英文文献资料
HindawiPublishingCorporation
JournalofSkinCancer
Volume2012,ArticleID741397,5pages
doi:10.1155/2012/741397
ClinicalStudy
BasalCellCarcinomainAsians:ARetrospectiveAnalysisofTen
Patients
MichaelG.Moore andRichardG.Bennett
1 2
1
2
SchoolofMedicine,IndianaUniversity,Indianapolis,IN46202-3082,USA
SchoolofMedicine,UniversityofCaliforniaatLosAngeles,LosAngeles,CA90095,USA
CorrespondenceshouldbeaddressedtoMichaelG.Moore,mgmoore@
Received31March2012;Accepted10May2012
AcademicEditor:M.Lebwohl
Copyright?2012M.G.MooreandR.G.Bennett. This is an open access article distributed under the Creative Commons
AttributionLicense,whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkis
properlycited.
Background.Fewstudieshavebeendonethatcharacterizebasalcellcarcinoma(BCC)inAsiansbecausethistumorisrelatively
uncommoninthispopulationgroup.Objective.TocharacterizeBCCinAsians.Methods.Weretrospectivelyexamined?fteen
patientvariablesandeighttumorvariablesoftenAsianpatientswithBCCandcomparedtheseresultstothoseofthirtymatched
CaucasiancontrolswithBCC.Results.Asiansdevelopedtheir?rstBCCatanolderagethantheageof?rstBCCinCaucasian
controls(68.9yearsversus58.3years;P 0.05).Duringtheirlifetime,AsianshadfewerBCCsthanthenumberofBCCsin
Caucasiancontrols(1.11versus5.41;P 0.02),despiteasimilarestimatedlifetimedailysunexposure(hours/day)forboth
groups.ComparedtoBCCsinCaucasiancontrols,ahigherpercentageofBCCsinAsianswereclinicallypigmented(50.0%versus
3.3%;P0.01).Conclusion.AsiansdevelopBCCslaterinlifeanddevelopfewerBCCsovertheirlifetimethanCaucasians,despite
similarestimatedlifetimedailysunexposure.This?ndingisprobablyduetoskinpigmentationinAsiansbeingmoreprotective
ofultravioletlightthanskinpigmentationinCaucasians.
1.Background
authors (RGB) from January 1992 to January 2001 were
identi?ed. All patient records were deidenti?ed prior to
performingaretrospectivereviewandconsequentlyInstitu-
tionalReviewBoardapprovalwasnotobtained.
Ba
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