Biological Effect of Leaf Aqueous Extract of Caesalpinia pyramidalis in Goats Naturally Infected with Gastrointestinal Nematodes英文文献资料.docVIP

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Biological Effect of Leaf Aqueous Extract of Caesalpinia pyramidalis in Goats Naturally Infected with Gastrointestinal Nematodes英文文献资料.doc

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Biological Effect of Leaf Aqueous Extract of Caesalpinia pyramidalis in Goats Naturally Infected with Gastrointestinal Nematodes英文文献资料

HindawiPublishingCorporation Evidence-BasedComplementaryandAlternativeMedicine Volume2012,ArticleID510391,6pages doi:10.1155/2012/510391 ResearchArticle BiologicalEffectofLeafAqueousExtractof CaesalpiniapyramidalisinGoatsNaturallyInfectedwith GastrointestinalNematodes RobertoRobsonBorges-dos-Santos, 1 JorgeA.Lo′pez, 2 LucianoC.Santos, 3 FaroukZacharias, 4 5 JorgeMaur′?cioDavid, JuceniPereiraDavid, 6 andFernandaWashingtondeMendonc?aLima 6 1 2 EscoladeMedicinaVeterin′aria,UniversidadeFederaldaBahia,40170-000Salvador,BA,Brazil ProgramadeP′os-Graduac??aoemBiotecnologiaIndustrial,InstitutodeTecnologiaePesquisa,UniversidadeTiradentes, 49032-490Aracaju,SE,Brazil 3 4 5 6 CentrodePesquisaGonc?aloMoniz-FIOCRUZ,40296-710Salvador,BA,Brazil EmpresaBaianadeDesenvolvimentoAgr′?cola,41635-150Salvador,BA,Brazil InstitutodeQu′?mica,UniversidadeFederaldaBahia,40170-290Salvador,BA,Brazil FaculdadedeFarm′acia,UniversidadeFederaldaBahia,41.170-280,Salvador,BA,Brazil CorrespondenceshouldbeaddressedtoFernandaWashingtondeMendonc?aLima,ferwlima@.br Received27October2011;Revised19January2012;Accepted20January2012 AcademicEditor:VincenzoDeFeo Copyright?2012RobertoRobsonBorges-dos-Santosetal.ThisisanopenaccessarticledistributedundertheCreativeCommons AttributionLicense,whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkis properlycited. Forty-eightgoatsnaturallyinfectedwithgastrointestinalnematodeswererandomlydividedintofourgroups(n =12):negative control(G1)(untreated),positivecontrol(G2)(treatedwithdoramectin,1mL/50Kgb.w.),andG3andG4treatedwith2.5and 5mg/Kgb.w.ofaleafaqueousextractofCaesalpiniapyramidalis(CP).Fecalandbloodsampleswereregularlycollectedforthe evaluationoffecaleggcount(FEC),hematologicalandimmunologicalparameterstoassesstheanthelminticactivity.Intreated animalswithCP,therewasnotedasigni?cantreductionof54.6and71.2%inthemeanFEC(P 0.05).AnincreaseinIgA levelswasobservedinG3andG4(P 0.05),duringtheexperimentalperiod,suggestin