Candida lusitaniae as an Unusual Cause of Recurrent Vaginitis and its Successful Treatment With Intravaginal Boric Acid英文文献资料.docVIP

Infect Dis Obstet Gynecol 2001;9:245–247 Candida lusitaniae as an unusual cause of recurrent vaginitis and its successful treatment with intravaginal boric acid Neil S. Silverman , Margie Morgan and W.S. Nichols 1 2 2 1 Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Burns Allen Research Institute, UCLA School of Medicine, Los Angeles, CA Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Burns Allen Research Institute, UCLA School of Medicine, Los Angeles, CA 2 Increasing use of short-course antifungal therapies in patients with recurrent vulvovaginitis may enable the emergence of less-common, more resistant yeast strains as vaginal pathogens. We report the case of a patient with chronically symptomatic and repeatedly treated vaginal candidiasis whose infection was attributable to Candida lusitaniae, a previously unreported cause of candidal vaginitis. Key words: VULVOVAGINITIS; VAGINITIS; CANDIDA; BORIC ACID CASE REPORT Thepatient was in good health, with no chronic medical conditions. She was taking no medica- tions. A total abdominal hysterectomy with ovarian preservation had been performed 17 years earlier for uterine leiomyomata. The patient reported no menopausal vasomotor symptoms, and was not taking hormone replacement therapy. Evaluation of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) levels had recently been performed in her referring doctor’s office and were not in the menopausal range. At the time of initial evaluation, the patient reported only minimal symptomatology. Exami- nation revealed no redness or swelling of the external genitalia or the vagina. No lesions or excoriations were present. The vaginal pH was 4.5, and microscopic examination of the vaginal secretions showed only normal-appearing epithe- lial cells with scattered large rod-form bacteri