Cancer, Fertility Preservation, and Future Pregnancy A Comprehensive Review英文文献资料.docVIP

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Cancer, Fertility Preservation, and Future Pregnancy A Comprehensive Review英文文献资料.doc

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Cancer, Fertility Preservation, and Future Pregnancy A Comprehensive Review英文文献资料

HindawiPublishingCorporation ObstetricsandGynecologyInternational Volume2012,ArticleID953937,11pages doi:10.1155/2012/953937 ReviewArticle Cancer,FertilityPreservation,andFuturePregnancy: AComprehensiveReview MichelleL.Matthews, 1 1 BradleyS.Hurst, 1 PaulB.Marshburn, andTerrySarantou 2 1 RebeccaS.Usadi, MargaretA.Papadakis, 1 1 2 DepartmentofObstetricsandGynecology,CarolinasMedicalCenter,P.O.Box32861,Charlotte, NC28232,USA BlumenthalCancerCenter,CarolinasMedicalCenter,1025MoreheadMedicalDrive,Charlotte, NC28204,USA CorrespondenceshouldbeaddressedtoMichelleL.Matthews,michelle.matthews@ Received13September2011;Accepted5December2011 AcademicEditor:EinatShalom-Paz Copyright?2012MichelleL.Matthewsetal.ThisisanopenaccessarticledistributedundertheCreativeCommonsAttribution License,whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperly cited. Giventheincreasesin5-yearcancersurvivalandrecentadvancesinfertilitypreservingtechnologies,anincreasingnumberof womenwithcancerarepresentingfordiscussionoffertilitypreservingoptions.Thisreviewwillsummarizetheriskofinfertility secondarytocancertreatment,availabletreatmentoptionsforfertilitypreservation,andtechniquestoreducefuturerisksfor patients. Concerns that will be addressed include the risk of the medications and procedures, the potential delay in cancer treatment,likelihoodofpregnancycomplications,aswellastheimpactoffuturepregnancyontherecurrenceriskofcancer. Recentadvancesinoocytecryopreservationandovarianstimulationprotocolswillbediscussed.Healthcareprovidersneedto beinformedofavailabletreatmentoptionsincludingtherisks,advantages,anddisadvantagesoffertilitypreservingoptionsto properlycounselpatients. 1.Introduction Fertility preservation is a rapidly evolving ?eld that includes medical and surgical treatments to decrease the impact of cancertreatments on futurefertility. Traditional fertilitypreservingtechniquesforpatientsundergoingradi- ationtreatmentincludedpelvicshieldingorsurg