射波刀治疗原发性肝癌328例初步结果分析.pdfVIP

现代肿瘤医学 2016 年06 月 第24 卷第 11 期 MODERN ONCOLOGY •Jun. 2016. VOL 24. NO. 11 • 1763 • 射波刀治疗原发性肝癌328 例初步结果分析 姚二华l ，梁平1 ，郑银燕2 ，刘建民1 ，韩 菲1 ，卢幻具3 ，吴发胜1 ，张钟群1 ， ~IJ 嘉毅I Outcome of patien恒 with primary liver cancer treated by cyberknife : Ar创rospective review of 328 cases 1 2 1 3 1 Yao Erhua , Liang Ping , Zheng Yinyan ,Liu Jianmin , Han Fei , Lu Huanzhen , Wu Fasheng , Zhang Zhongqun , 1 Liu Jiayi I Department .01 Radiotherapy; 2Department 01 Preventive Health Care; 3Depart阳nt 01 Cyberknife ,Ruikang Ho机时， Guangxi College 01 Traditional Chinese Medicine , Guangxi Nanning 530011 , China. [Abstract] Objective: To investigate the outcomes and complications of cybe由战 in patients with primary liver C四cer. Methods: Data of 328 patients with primary liver cancer treated by cyberknife was analyzed , including 288 males and 40 females. The age of patients ranged from 21 to 79 years old ,with average age 52. 5 years old. The radio- therapy fractions were 1 - 10( average 4. 35) . The total dose was 24.5 - 52Gy ( average 42. 7Gy) . Isodose curve was from 56% - 90% (average 69.3% ). Results: The follow - up time was from 6 mon由s to 74 months ( average 22 months). According to mRECIST standard , CT/ MR were reviewed after 6 months of treatment ,with complete re- mission ( CR ) in 29 cases (8. 8 % ) ,partial remission ( PR) in 201 cases ( 6 1. 3 % ) ,stable disease ( SD) in 63 cases (19.2% ) ,progress disease( PD) in 35 cases( 10. 7% ). Median progression free survival was 14.38 months ,the me- dian overall survival 17. 3 mon由s. Conclusion: Cyberknife is an effective and safe treatment of prim缸y liver cancer. [Key words] prim町liver ca配叽cybe由life