Equal Graph Partitioning on Estimated Infection Network as an Effective Epidemic Mitigation Measure 英文参考文献.docVIP

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Equal Graph Partitioning on Estimated Infection Network as an Effective Epidemic Mitigation Measure 英文参考文献.doc

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Equal Graph Partitioning on Estimated Infection Network as an Effective Epidemic Mitigation Measure 英文参考文献

EqualGraphPartitioningonEstimatedInfectionNetwork asanEffectiveEpidemicMitigationMeasure JeremyHadidjojo,SiewAnnCheong* DivisionofPhysicsandAppliedPhysics,SchoolofPhysicalandMathematicalSciences,NanyangTechnologicalUniversity,Singapore,RepublicofSingapore Abstract Controllingsevereoutbreaksremainsthemostimportantproblemininfectiousdiseasearea.Withtime,thisproblemwill onlybecomemoresevereaspopulationdensityinurbancentersgrows.Socialinteractionsplayaveryimportantrolein determininghowinfectiousdiseasesspread,andorganizationofpeoplealongsociallinesgivesrisetonon-spatialnetworks inwhichtheinfectionsspread.Infectionnetworksaredifferentfordiseaseswithdifferenttransmissionmodes,butarelikely tobeidenticalorhighlysimilarfordiseasesthatspreadthesameway.Hence,infectionnetworksestimatedfromcommon infectionscanbeusefultocontainepidemicsofamoreseverediseasewiththesametransmissionmode.Herewepresenta proof-of-concept study demonstrating the effectiveness of epidemic mitigation based on such estimated infection networks. We first generate artificial social networks of different sizes and average degrees, but with roughly the same clusteringcharacteristic.WethenstartSIRepidemicsonthesenetworks,censorthesimulatedincidences,andusethemto reconstructtheinfectionnetwork.Wethenefficientlyfragmenttheestimatednetworkbyremovingthesmallestnumberof nodesidentifiedbyagraphpartitioningalgorithm.Finally,wedemonstratetheeffectivenessofthistargetedstrategy,by comparingitagainsttraditionaluntargetedstrategies,inslowingdownandreducingthesizeofadvancingepidemics. Citation:HadidjojoJ,CheongSA(2011)EqualGraphPartitioningonEstimatedInfectionNetworkasanEffectiveEpidemicMitigationMeasure.PLoSONE6(7): e22124.doi:10.1371/journal.pone.0022124 Editor:MichaelB.Fessler,NationalInstituteofEnvironmentalHealthSciences,UnitedStatesofAmerica ReceivedApril15,2011;AcceptedJune15,2011;PublishedJuly22,2011 Copyright:?2011Hadidjojo,Cheong.Thisisanopen-accessarticledistributedunderthetermsoftheCreativeCommonsAttributionLic