Osmotic response tests on erythrocytes for the detection of double muscle carriers in cattle 英文参考文献.docVIP

OSMOTIC RESPONSE TESTS ON ERYTHROCYTES FOR THE DETECTION OF DOUBLE MUSCLE CARRIERS IN CATTLE 1() W. A. KING, PARVATHI K. BASRUR, R. G. BROWN R T. BERG * Dpt. of Animal and Poultry Science, University of Guelph, Ontario, Canada ** Dpt. of Animal science, University of Alberta, Erythrocyte harvested from heparinized whole blood of a group of cattle of various breeds including overtly- double muscled animals and more revealed an increased rate of hemolysis on exposure to osmotic shock as Charolais cattle. There is also a clearcut distinction between the rate of hemolysis of double muscled animals and normal carriers detected because they have some transmitted the trait. They all seem in our samples to be heterozygotes in the generally admitted hypothesis that double muscling is due to a simple mendelian factor. It is hence suggested that the erythrocyte fragility test described in this report may be used for the identification of carriers which are often difficult to distinguish from normal animals on the basis of morphologic criteria. L AUVERGNE et al., 1968 for review). Double muscling syndrome (hereditary muscular hypertrophy) characterized by massive muscles, reduced subcutaneous and intramuscular fat deposits, thin skin and light bones, has been reported to be When fully expressed, the condition is easily recognized by the increased musculature, nota- (t) of the Master’s Thesis submitted to Hereditary Muscular Hypertrophy (Double Muscling) in Beef the University of Guelph by Cattle). (i975:  bly in the hindquarters and by the characteristic crease in the muscle caused by the thin skin and reduced subcutaneous fat. Although the carriers of this trait are desirable because of their relatively fast rate of growth during the first year and the quality of the carcasses, double muscled dquo; fetus often causes diffi- a culty at parturition, and after birth, the affected animals tend to be extremely susceptible to stress. These problems, coup