Organophosphorus Chemistry for the Synthesis of Dendrimers 英文参考文献.docVIP

Molecules 2012, 17, 13605-13621; doi:10.3390/molecules171113605 OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Review Organophosphorus Chemistry for the Synthesis of Dendrimers Anne-Marie Caminade 1,2,*, Régis Laurent 1,2, Maria Zablocka 1,2,3 and Jean-Pierre Majoral 1,2 1 CNRS, LCC (Laboratoire de Chimie de Coordination), 205 route de Narbonne, BP44099, F-31077 Toulouse Cedex 4, France; E-Mails: rlaurent@lcc-toulouse.fr (R.L.); majoral@lcc-toulouse.fr (J.-P.M.) 2 Université de Toulouse, UPS, INPT, F-31077 Toulouse Cedex 4, France 3 Centre of Molecular and Macromolecular Studies, The Polish Academy of Sciences, Sienkiewicza 112, 90363 Lodz, Poland; E-Mail: zabloc@cbmm.lodz.pl * Author to whom correspondence should be addressed; E-Mail: caminade@lcc-toulouse.fr; Fax: +33-561-553-003. Received: 31 October 2012; in revised form: 9 November 2012 / Accepted: 12 November 2012 / Published: 16 November 2012 Abstract: Dendrimers are multifunctional, hyperbranched and perfectly defined macromolecules, synthesized layer after layer in an iterative manner. Besides the nature of the terminal groups responsible for most of the properties, the nature of the internal structure, and more precisely of the branching points, is also of crucial importance. For more than 15 years, we have demonstrated that the presence of phosphorus atom(s) at each branching point of the dendrimeric structure is particularly important and highly valuable for three main reasons: (i) the versatility of phosphorus chemistry that allows diversified organochemistry for the synthesis of dendrimers; (ii) the use of 31P-NMR, which is a highly valuable tool for the characterization of dendrimers; (iii) some properties (in the fields of catalysis, materials, and especially biology), that are directly connected to the nature of the internal structure and of the branching points. This review will give an overview