Prevalence of insulin resistance and its association with metabolic syndrome criteria among Bolivian children and adolescents with obesity 英文参考文献.docVIP
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Prevalence of insulin resistance and its association with metabolic syndrome criteria among Bolivian children and adolescents with obesity 英文参考文献
BMC Pediatrics
BioMedCentral
Research article
Open Access
Prevalence of insulin resistance and its association with metabolic
syndrome criteria among Bolivian children and adolescents with
obesity
Margoth Caceres?, Carlos G Teran*?, Susana Rodriguez and Marcos Medina
Address: Department of General Pediatrics, Centro Pediatrico Albina Pati?o, Cochabamba, Bolivia
Email: Margoth Caceres - margothcm@; Carlos G Teran* - carteran79@; Susana Rodriguez - pva10@;
Marcos Medina - rolo100000@
* Corresponding author ?Equal contributors
Published: 12 August 2008
Received: 12 April 2008
Accepted: 12 August 2008
BMC Pediatrics 2008, 8:31
doi:10.1186/1471-2431-8-31
This article is available from: /1471-2431/8/31
? 2008 Caceres et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Obesity is a one of the most common nutritional disorder worldwide, clearly
associated with the metabolic syndrome, condition with implications for the development of many
chronic diseases.
In the poorest countries of Latin America, malnourishment is still the most prevalent nutritional
problem, but obesity is emerging in alarming rates over the last 10 years without a predictable
association with metabolic syndrome.
The objective of our study was to determine the association between insulin-resistance and
components of the metabolic syndrome in a group of Bolivian obese children and adolescents. The
second objective was determining the relation of acanthosis nigricans and insulin-resistance.
Methods: We studied 61 obese children and adolescents aged between 5 and 18 years old. All
children underwent an oral glucose tolerance test and fasting blood sample was also obtained to
measure insulin, HDL
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