Prevalence, Clinical Staging and Risk for Blood-Borne Transmission of Chagas Disease among Latin American Migrants in Geneva, Switzerland 英文参考文献.docVIP

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Prevalence, Clinical Staging and Risk for Blood-Borne Transmission of Chagas Disease among Latin American Migrants in Geneva, Switzerland 英文参考文献.doc

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Prevalence, Clinical Staging and Risk for Blood-Borne Transmission of Chagas Disease among Latin American Migrants in Geneva, Switzerland 英文参考文献

Prevalence,ClinicalStagingandRiskforBlood-Borne TransmissionofChagasDiseaseamongLatinAmerican MigrantsinGeneva,Switzerland YvesJackson1*,LaurentGe′taz1,HansWolff1,MaryliseHolst1,AnneMauris2,Aglae′ Tardin3 ,Juan Sztajzel4,Vale′rieBesse5,LouisLoutan3,Jean-MichelGaspoz1,JeanJannin6,PedroAlbajarVinas6, AlejandroLuquetti7,Franc?oisChappuis3 1DivisionofPrimaryCareMedicine,DepartmentofCommunityMedicineAndPrimaryCare,UniversityHospitalsofGenevaandFacultyofMedicine,GenevaUniversity, Geneva,Switzerland,2DivisionofHumanitarianandInternationalMedicine,DepartmentofCommunityMedicineandPrimaryCare,UniversityHospitalsofGenevaand FacultyofMedicine,GenevaUniversity,Geneva,Switzerland,3DepartmentofGeneticsandLaboratory,UniversityHospitalsofGenevaandFacultyofMedicine,Geneva University, Geneva, Switzerland, 4Division of Cardiology, Department of General Internal Medicine, University Hospitals of Geneva and Faculty of Medicine, Geneva University,Geneva,Switzerland,5DepartmentofRadiology,UniversityHospitalsofGenevaandFacultyofMedicine,GenevaUniversity,Geneva,Switzerland,6Controlof Neglected Tropical Diseases, World Health Organization, Geneva, Switzerland, 7Laboratorio de Chagas, Hospital das Clinicas, Universidade Federal de Goia′s, Goiania, Brazil Abstract Background:MigrationofLatinAmericanstotheUSA,CanadaandEuropehasmodifiedChagasdiseasedistribution,but dataonimportedcasesandonrisksoflocaltransmissionremainscarce.Weassessedtheprevalenceandriskfactorsfor Chagasdisease,stagedthediseaseandevaluatedattitudestowardsbloodtransfusionandorgantransplantamongLatin AmericanmigrantsinGeneva,Switzerland. Methodology/Principal Findings: This cross-sectional study included all consecutive Latin American migrants seeking medical care at a primary care facility or attending two Latino churches. After completing a questionnaire, they were screened for Chagas diseasewithtwo serologicaltests (Biome′rieuxELISA cruzi; Biokit BioelisaChagas). Infected subjects underwent a complete medical work-up. P