Prior Knowledge, Older Age, and Higher Allowance Are Risk Factors for Self-Medication with Antibiotics among University Students in Southern China 英文参考文献.docVIP

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Prior Knowledge, Older Age, and Higher Allowance Are Risk Factors for Self-Medication with Antibiotics among University Students in Southern China 英文参考文献.doc

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Prior Knowledge, Older Age, and Higher Allowance Are Risk Factors for Self-Medication with Antibiotics among University Students in Southern China 英文参考文献

PriorKnowledge,OlderAge,andHigherAllowanceAre RiskFactorsforSelf-MedicationwithAntibioticsamong UniversityStudentsinSouthernChina HuiPan1,BinglinCui1,DanguiZhang1,JeremyFarrar1,2,FriedaLaw3,WilliamBa-Thein1,4* 1Shantou-Oxford Clinical Research Unit, ShantouUniversity Medical College, Shantou, Guangdong,P.R.China, 2Oxford University Clinical Research Unit, Hospital for TropicalDiseases,WellcomeTrustMajorOverseasProgramme,HoChiMinhCity,VietNam,3ConsultantOffice,ShantouUniversityMedicalCollege,Shantou,Guangdong, P.R.China,4DepartmentofMicrobiologyandImmunology,ShantouUniversityMedicalCollege,Shantou,Guangdong,P.R.China Abstract Background:Self-medicationwithantibiotics(SMA)hasbeenreportedamonguniversitystudentsinmanycountries,but littleresearchhasbeendoneonthisissueinChina.Theobjectiveofthisstudywastoevaluateknowledgeandbehaviorsof universitystudentsandriskfactorsconcerningSMA. Methodology/Principal Findings: Using a novel questionnaire-based data collection instrument, an anonymous online surveywasconductedwiththestudentsofShantouUniversity(STU),auniversitycomprising8schools/collegesineastern Guangdong, China. Of 1,300 respondents (13.8% of total eligible participants), 47.8% had self-treated with antibiotics. Logistic regression analysis identified prior knowledge of antibiotics (PKA), older age, and higher monthly allowance as independent risk factors for SMA. PKA significantly influenced students’ knowledge about antibiotics, their uses, and common adverse reactions (all p,0.05). Among self-medicated students, 61.7% used antibiotics at least twice in the previousyear.Communitypharmacieswerethemajorsourceofself-prescribedantibiotics.Reportedcommonindications forSMAweresorethroat(59.7%),fever(38.2%),cough(37.4%),runnynose(29.3%),andnasalcongestion(28.7%).While 74.1%ofself-medicationepisodeswerebasedonstudents’ownexperiences,only31.1%ofstudentsclaimedtounderstand thepackageinsert.Alterationofantibioticsanddosageduringthecourseofself-treatmentwasmadeby63.8%and55.6% o