Screening of Natural Antioxidants from Traditional Chinese Medicinal Plants Associated with Treatment of Rheumatic Disease 英文参考文献.docVIP

Molecules 2010, 15, 5988-5997; doi:10.3390/moleculeOPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Article Screening of Natural Antioxidants from Traditional Chinese Medicinal Plants Associated with Treatment of Rheumatic Disease Ren-You Gan 1, Lei Kuang 1, Xiang-Rong Xu 2, Yuan Zhang 1, En-Qin Xia 1, Feng-Lin Song 1 and Hua-Bin Li 1,* 1 Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China; E-Mails: ganry_zsu@ (R.G.); kwung_1121@ (L.K.); fly198013@ (Y.Z.); enqinxia@163.com (E.X.); sflin1986@163.com (F.S.) 2 Key Laboratory of Marine Bio-resources Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China; E-Mail: xuxr2000@ (X.X.) * Author to whom correspondence should be addressed; E-Mail: lihuabin@; Tel.: +86-20-8733-2391; Fax: +86-20-8733-0446. Received: 21 April 2010; in revised form: 10 August 2010 / Accepted: 13 August 2010 / Published: 30 August 2010 Abstract: In order to find new sources of natural antioxidants, the antioxidant capacities of 50 medicinal plants associated with treatment of rheumatic diseases were systemically evaluated using the ferric-reducing antioxidant power (FRAP) and Trolox equivalent antioxidant capacity (TEAC) assays, and their total phenolic contents were measured by the Folin–Ciocalteu method. Their antioxidant activities of some of these plants were analyzed for the first time. The FRAP and TEAC assay results suggested that the antioxidant compounds in these plants possessed free radicals scavenging activity and oxidant reducing power. A positive linear correlation between antioxidant capacities and total phenolic contents implied that phenolic compounds in these plants could be the main components contributing to the observed activities. The results showed that Geranium wilfordii, Lora