Skeletal muscle oxygen saturation does not estimate mixed venous oxygen saturation in patients with severe left heart failure and additional severe sepsis or septic shock 英文参考文献.docVIP
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Skeletal muscle oxygen saturation does not estimate mixed venous oxygen saturation in patients with severe left heart failure and additional severe sepsis or septic shock 英文参考文献
Available online /content/11/1/R6
Research
Open Access
Vol 11 No 1
Skeletal muscle oxygen saturation does not estimate mixed
venous oxygen saturation in patients with severe left heart failure
and additional severe sepsis or septic shock
Matej Podbregar and Hugon Mo?ina
Clinical Department for Intensive Care Medicine, University Clinical Centre, Zaloska 7, 1000 Ljubljana, Slovenia
Corresponding author: Matej Podbregar, Matej.Podbregar@guest.arnes.si
Received: 13 Oct 2006 Revisions requested: 22 Nov 2006 Revisions received: 30 Nov 2006 Accepted: 16 Jan 2007 Published: 16 Jan 2007
Critical Care 2007, 11:R6 (doi:10.1186/cc5153)
This article is online at: /content/11/1/R6
? 2007 Podbregar and Mo?ina; licensee BioMed Central Ltd.
This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Introduction Low cardiac output states such as left heart failure
are characterized by preserved oxygen extraction ratio, which is
in contrast to severe sepsis. Near infrared spectroscopy (NIRS)
healthy volunteers (P = 0.02). In group A StO correlated with
2
SvO (r = 0.689, P = 0.002), although StO overestimated
2
2
SvO (bias -2.3%, precision 4.6%). In group A changes in StO
2
2
2
allows
noninvasive
estimation
of
skeletal
muscle
tissue
correlated with changes in SvO (r = 0.836, P 0.001;ΔSvO
2
oxygenation (StO ). The aim of the study was to determine the
= 0.84 × ΔStO - 0.67). In group B important differences
2
2
relationship between StO and mixed venous oxygen saturation
between these variables were observed. Plasma lactate
2
(SvO2) in patients with severe left heart failure with or without
concentrations correlated negatively with StO values only in
2
additional severe sepsis or septic shock.
group A (r = -0.522, P = 0.009;
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