Two years follow-up study of the pain-relieving effect of gold bead implantation in dogs with hip-joint arthritis 英文参考文献.docVIP

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Two years follow-up study of the pain-relieving effect of gold bead implantation in dogs with hip-joint arthritis 英文参考文献.doc

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Two years follow-up study of the pain-relieving effect of gold bead implantation in dogs with hip-joint arthritis 英文参考文献

Acta Veterinaria Scandinavica BioMedCentral Research Open Access Two years follow-up study of the pain-relieving effect of gold bead implantation in dogs with hip-joint arthritis Gry T J?ger*1, Stig Larsen2, Nils S?li3 and Lars Moe1 Address: 1Department of Companion Animal Clinical Sciences, Norwegian School of Veterinary Science, Post Box 8146 Dep., N-0033 Oslo, Norway, 2Department of Production Animal Clinical Sciences, Norwegian School of Veterinary Science, Post Box 8146 Dep., N-0033 Oslo, Norway and 3Department of Food Safety and Infection Biology, Norwegian School of Veterinary Science, Post Box 8146 Dep., N-0033 Oslo, Norway Email: Gry T J?ger* - gry.jaeger@veths.no; Stig Larsen - Stig.Larsen@veths.no; Nils S?li - Nils.Soeli@veths.no; Lars Moe - Lars.Moe@veths.no * Corresponding author Published: 23 March 2007 Received: 20 September 2006 Accepted: 23 March 2007 Acta Veterinaria Scandinavica 2007, 49:9 doi:10.1186/1751-0147-49-9 This article is available from: /content/49/1/9 ? 2007 J?ger et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Seventy-eight dogs with pain from hip dysplasia participated in a six-month placebo-controlled, double-blinded clinical trial of gold bead implantation. In the present, non-blinded study, 73 of these dogs were followed for an additional 18 months to evaluate the long-term pain-relieving effect of gold bead implantation. The recently-published results of the six month period revealed that 30 of the 36 dogs (83%) in the gold implantation group showed significant improvement (p = 0.02), included improved mobility and reduction in the signs of pain, compared to the placebo group (60% improvement). In the long-term two-year follow-up study, 66 of the 73 dog