Ulysses - an application for the projection of molecular interactions across species 英文参考文献.docVIP

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Ulysses - an application for the projection of molecular interactions across species 英文参考文献.doc

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Ulysses - an application for the projection of molecular interactions across species 英文参考文献

Open Access So are 2005KemmeretVoal.luftw6, Issue 12, Article R106 Ulysses - an application for the projection of molecular interactions across species Danielle Kemmer*?, Yong Huang?, Sohrab P Shah?￥, Jonathan Lim?, Jochen Brumm?, Macaire MS Yuen?, John Ling?, Tao Xu?, Wyeth W Wasserman?§ and BF Francis Ouellette?§? Addresses: *Center for Genomics and Bioinformatics, Karolinska Institutet, 171 77 Stockholm, Sweden. ?Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver V5Z 4H4, BC, Canada. ?UBC Bioinformatics Centre, University of British Columbia, Vancouver V6T 1Z4, BC, Canada. §Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada. ?Michael Smith Laboratories, University of British Columbia, Vancouver V6T 1Z4, BC, Canada. ￥Department of Computer Science, University of British Columbia, Vancouver V6T 1Z4, BC, Canada. Correspondence: Wyeth W Wasserman. E-mail: wyeth@cmmt.ubc.ca Published: 2 December 2005 Received: 23 February 2005 Revised: 3 August 2005 Accepted: 8 November 2005 Genome Biology 2005, 6:R106 (doi:10.1186/gb-2005-6-12-r106) The electronic version of this article is the complete one and can be found online at /2005/6/12/R106 ? 2005 Kemmer et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. ProjectingpUlyssesmolecular, a new sointeractionsftware for theacrossparallspeciesel analysis and display of protein interactions detected in various species, is described./p Abstract We developed Ulysses as a user-oriented system that uses a process called Interolog Analysis for the parallel analysis and display of protein interactions detected in various species. Ulysses was designed to perform such Interolog Analysis by the projection of