Utility of the Framingham risk score to predict the presence of coronary atherosclerosis in patients with rheumatoid arthritis 英文参考文献.docVIP

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Utility of the Framingham risk score to predict the presence of coronary atherosclerosis in patients with rheumatoid arthritis 英文参考文献.doc

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Utility of the Framingham risk score to predict the presence of coronary atherosclerosis in patients with rheumatoid arthritis 英文参考文献

Available online /content/8/6/R186 Research article Open Access Vol 8 No 6 Utility of the Framingham risk score to predict the presence of coronary atherosclerosis in patients with rheumatoid arthritis Cecilia P Chung1, Annette Oeser1, Ingrid Avalos1, Tebeb Gebretsadik2, Ayumi Shintani2, Paolo Raggi3, Tuulikki Sokka1,4, Theodore Pincus1 and C Michael Stein1,5 1Department of Medicine, Vanderbilt University School of Medicine, 1161 21st Ave., Nashville, TN 37232, USA 2Department of Biostatistics, Vanderbilt University School of Medicine, S-2323 Medical Center North, Nashville, TN 37232, USA 3Department of Medicine, Division of Cardiology, Emory University School of Medicine, 1365 Clifton Road NE, AT-504, Atlanta, GA 30322 4Jyv?skyl? Central Hospital, 40620 Jyv?skyl?, Finland 5Department of Pharmacology, Vanderbilt University School of Medicine, 542 RRB, Nashville, TN 37232, USA Corresponding author: C Michael Stein, michael.stein@ Received: 24 Jul 2006 Revisions requested: 23 Aug 2006 Revisions received: 25 Oct 2006 Accepted: 14 Dec 2006 Published: 14 Dec 2006 Arthritis Research Therapy 2006, 8:R186 (doi:10.1186/ar2098) This article is online at: /content/8/6/R186 ? 2006 Chung et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract The prevalence of ischemic heart disease and atherosclerosis is increased in patients with rheumatoid arthritis (RA). In the general population, but not in patients with systemic lupus erythematosus, the Framingham risk score identifies patients at increased cardiovascular risk and helps determine the need for preventive interventions. We examined the hypothesis that the Framingham score is increased and associated with coronary- artery atherosclerosis in patients with R