严重外伤性脾破裂切除加自体脾移植的临床疗效.pdfVIP

·外科研究· 2 0 1 5 年 3 月 第 5 卷 第 6 期 严重外伤性脾破裂切除加自体脾移植的临床疗效 任伟耀    陈德明    范海鹰    梁健雄    刘健雄   广东省鹤山市人民医院外科一区，广东鹤山 529700 [ 摘要 ] 目的 探讨严重外伤性脾破裂切除加自体脾移植的临床疗效。 方法 选取我院 2013 年 1 月 ~2014 年 8 月入院手术治疗的 35 例外伤性脾破裂患者做为研究对象。按照入院顺序随机分为治疗组 17 例与对照组 18 例，治疗组患者应用脾切除加脾移植术治疗，对照组患者仅应用脾切除无移植治疗。对比两组患者的脾 功能恢复及血小板变化情况。 结果 治疗组患者的体液免疫与细胞免疫水平显著优于对照组患者，差异有 统计学意义（P ＜ 0.05）。治疗组患者手术后血小板增幅低于对照组，差异有统计学意义（P ＜ 0.05）。治疗 组患者的并发症发生率显著低于对照组患者，差异有统计学意义（P ＜ 0.05）。 结论 通过严重外伤性脾破 裂患者实施脾切除加自体脾移植治疗，脾功能恢复良好，血小板变化小，临床值得广泛推广应用。 [ 关键词 ] 严重外伤；脾破裂；自体脾移植；血小板 [ 中图分类号 ] R657.6 [ 文献标识码 ] B [ 文章编号 ] 2095-0616（2015）06-144-03 The clinical efficacy of resection and splenic transplantation in severe traumatic spleen rupture REN  Weiyao    CHEN  Deming    FAN  Haiying    LIANG  Jianxiong    LIU  Jianxiong  The First Surgical Department, Peoples Hospital of Heshan City in Guangdong Province, Heshan 529700, China [Abstract]Objective To investigate the clinical efficacy of resection and autologous transplantation in severe traumatic rupture of the spleen. Methods 35 hospitalized surgical treatment of patients with traumatic rupture in our hospital from January 2013 to August 2014 were selected as the object of study. According to the order of admission they were randomly divided into a treatment group in 17 cases and a control group in 18 cases, patients in the treatment group received spleen resection and spleen transplantation therapy, the control group only received transplant therapy without spleen transplantation. The function of splenic recovery and changes of platelet between the two groups were compared. Results The level of humoral immunity and cellular immunity in treatment group was significantly better tha