原发性肝癌TACE术后严重并发症原因及预防.pdfVIP

介入放射学杂志组附华门月第 17 卷第 11 期 J Intervent Radiol 2ω8， Vo 1.l7 , No.ll …773 … ·肿瘤介入 Tumor intervention. 原发性肝癌 TACE 术后严重并发症 原因及预防 赵广生，徐克，梁松年， ~洪英，冯博，杨福玲 {摘要] 阔的 探讨原发性肝痛行经导管肝动脉化疗徐黎术后严囊并发疲的原因及预防。方法 2ω5 年 1 月 -2∞7 年7 月，573 例原发性肝癌患者行 1252 次肝动脉化疗梭寨术，术后针对发生的并发 症，给予积极泊疗，问时结合~化及影像学梭衡，擦讨严黛并发疲出现的原因及预防措施。结巢 并发症 有上消化道出JiD. 3 例、急性肝功能衰竭 6 例(死亡 l 例)、肺枪草草 l 例，JlJ! 汁瘸 2 例、!I!!囊袋 4 例、商穿孔 并死亡 1 例。结论 经军事管肝动脉化疗栓塞术治疗原发性肝癌出现的严意并发症与水前肝功能较蒙、门 静脉高压、化疗检塞药物剂噎过大、药物反流及异位枪塞等有关。重视TACE 术时机的选择，采用规范化 的介入治疗措施.可以避免或减少严重并发症。 I 关键词] 原发性肝癌;肝动脉化疗栓塞术:并发症 中团分类号:民735.7 文献标识码:A 文章编号:1ω8-794X(2∞8)幽 11-0773心3 Ca翩翩 and prevention of serious complication a伽r trans佣theter arteria1 chemoembolization for primary hepa锐c carcinoma ZHAO Cuang-sheng, XU Ke. LlANC So咆叩棚， SU Hong节ng， FENG 80 , YANG Fu-ling. 。印刷ment of Radiology. First A.ffilWt.ed Hospit aJ, China Medíc aJ Vniversity. Shenycmg 110001 , China [Abstract] Objec创刊 To analyze the etiological factolS and prevent沁n of serious complications after transcatheter arterial chemoembolization (TACE )for primary hepatic carcinoma(PHC). Methods A con创cu­ ti附如up of 573 patients with PHC receíved a toωof 1252 TACE procedures form Janu叫 2∞5 to July 2ω7. All patíents with complication were treated íntensively together with ímaging and biochemical ex.aminatior脯. in order to study the cau自es and preventive meωu陀s of the serious complications. Results After all , the record revealed 3 cas盼。，{ upper gastroint盼tival hemormage , 6 cωes of acute hepatic failure with one death , 1 c刷晤。f pulmonary ernbolism , 4 c偏es of cholecystitis; 2 c部es of intrahepatic bilorna and one died for gastric perforation. Cond田ions Severe complication with TACE for PHC míght be caused by existed p∞r líver function , portal hypertension , high dose of the chemother百.peutic agent ，命ug reflux or 创to