17种抗菌药物对儿科常见致病菌敏感性分析.docVIP

17种抗菌药物对儿科常见致病菌敏感性分析 【摘要】 目的：了解抗菌药物药敏现状，为抗菌药物临床合理使用提供资料。方法：统计湖南省郴州市第一人民 医院 儿童医院2007年住院患儿8种检出菌对17种抗菌药物的药敏试验结果并与其他地区结果比较。结果：G+球菌对万古霉素、亚胺培南西司他丁、氨苄西林舒巴坦、头孢噻肟、头孢唑林、头孢呋辛、头孢他啶、苯唑西林、青霉素、红霉素敏感率分别为99.3%、97.7%、89.0%、87.3%、86.9%、84.6%、80.8%、60.3%、45.2%、36.7%；G-杆菌对头孢他啶、氯霉素、亚胺培南西司他丁、头孢哌酮、氨曲南、头孢噻肟、哌拉西林、头孢曲松、氨苄西林舒巴坦、头孢呋辛、头孢噻吩、氨苄西林敏感率分别为76.9%、74.5%、68.2%、58.2%、53.5%、51.5%、51.1%、36.9%、33.1%、15.2%、9.6%、7.8%；G-杆菌对头孢曲松、头孢噻肟、头孢哌酮敏感率较其他地区低，对头孢他啶敏感率高；G+球菌对青霉素、头孢唑林、头孢噻肟、苯唑西林、氨苄西林/舒巴坦敏感率高；检出菌对万古霉素、亚胺培南西司他丁敏感率相当。结论：要加强临床分离菌对抗菌药物敏感性监测。 【关键词】 抗菌药物；儿童；药敏实验 An analysis on the sensitivity of 17 antibacterials to pathogenic bacteria commonly found in children LIN Jie1, LIU Qiaotu2, PENG Huabao1(1. The Childrens Hospital of First Peoples Hospital of Chenzhou, Hunan Province, Hunan Chenzhou 423000, China; 2. The Central Hospital of First Peoples Hospital of Chenzhou, Hunan Province, Hunan Chenzhou 423000, China) ［Abstract］ Objective: To get information on the current status of antibiotics and to provide data for rational use of these drugs. Methods: The results of drug sensitive tests in inpatients of the childrens hospital were statistically processed. The tests covered 17 antibiotics and the results were compared with those obtained by other hospitals. Results: The sensitive rates of G+ cocci to vancomycin, imipenemcilastatin, ampicillinsulbactam, cefotaxime, cefazolin, cefuroxime, ceftazidime, oxacillin, benzylpenicillin, erythromycin were 99.3%, 97.7%, 89.0%, 87.3%, 86.9%, 84.6%, 80.8%, 60.3%, 45.2%, 36.7% amd of G- bacilli to ceftazidime, chloramphenicol, imipenemcilastatin, cefoperazone, aztreonam, cefotaxime, piperacillin, ceftraxone, ampicillinsulbactam, cefuroxime, cephalothin, ampicillin were 76.9%, 74.5%, 68.2%, 58.2%, 53.5%, 51.5%, 51.1%, 36.9%, 33.1%, 15.2%, 9.6%, 7.8%, respectively. The sensitive rates of G- bacilli to ceftriaxone, cefotaxime, cefoperazone were lower than those in other hospitals; the sensitive rates of G+ cocci to benzylpenicillin, cefazolin, cefotaxi