普瑞巴林和加巴喷丁治疗带状疱疹后遗神经痛的成本一效果分析_闫军.pdfVIP

1 2 1 (1 250001 2 250022) [] - - 1.18~2.7MD1.31[95%CI1.181.44] 50%150mg/d26.19%300mg/d27.01%NNT 150mg/d5.69300mg/d5.44 2.0~2.4MD1.29[95%CI1.041.54] 50%1800mg/d29.91%2400mg/d34.26%NNT 1800mg/d 4.732400mg/d4.82MD0.89[95%CI 0.541.24]- 150mg/dC/E 62.24CN 9274.70300mg/dC/E 114.66CN 16847.681800 mg/d C/E 22.02CN 3114.712400mg/d C/E 26.91CN 4443.56 [] meta- [] 053181273111E-mail yjcsl@163.com 1 Cost-effectiveness Analysis of Pregabalin and Gabapentin in the Treatment of Post-herpetic Neuralgia 1 2 1 YAN Jun , CHEN Sheng-li , SHI Ke-shi (1 Jinan City Hospital for Skin Diseases Prevention and TreatmentJinan 250001, China; 2 Shandong Provincial Institute of Dermatology and Venereology Jinan250022 China) [ABSTRACT] Objective: To evaluate the cost-effectiveness ratios of pregabalin and gabapentin in the treatment of post-herpetic neuralgia (PHN). Methods: The reports on pregabalin and gabapentin in the treatment of PHN with randomizeddouble-blind and placebo-controlled design were collectedThe therapeutic effects of two drugs were compared and conducted with cost-effectiveness analysis. Results: Average daily pain score decreased from 1.18 to 2.7 an average day with pregabalin and placebo, combination effect size MD was 1.31[95%CI1.181.44]. Two dose of pregabalin [150mg/d26.19%and 300