水溶性量子点荧光探针的制备及其在食品分析检测中的应用.pdfVIP

Abstract Quantum dots, as a new pattern of fluorescent probes, have a great deal of advantages such as broad excitation spectrum, narrow-band emission spectrum, high chemical stability compared to the traditional fluorescent dyes. Quantum dots showed broad application prospects in the fields of life science, analytical chemistry, materials science and immunology in recent years. The work of predecessor was summarized such as preparation, characterization and application in detection of food safety of quantum dots. (1) The first chapter briefly introduced the basic characteristics, the synthesis methods and the surface modification methods of the quantum dots, and then gave a brief overview of the research progress and application prospects of quantum dots in food detection. (2) In this chapter, a simple and sensitive method based on the enhancement of the fluorescence intensity of thioglycolic acid-capped CdSe quantum dots is proposed for the determination of Sudan I. That UV-visible spectrophotometer 、fluorescence spectroscopy and transmission electron microscopy(TEM) were used to characterize the QDs. With the increment of the concentration of Sudan I, it gives a calibration graph linear in the range of 3×10-7mol/L-8×10-6mol/L. The obtained tropics equation is F/F =1.538C+2.689, with the correlation coefficient of 0.9962 and the detection limit of 0 -7 1×10 mol/L. The measurement has been applied to the determination of Sudan I in hot chili powder, and the recovery was 94.11%-104.86%. (3) On the basis of the second chapter, we synthesized of the core-shell CdSe /ZnS quantum dots. A novel method for determination of met