_女性下生殖道HPV感染与宫颈上皮内瘤变及宫颈癌关系的病理研究.pdf

20 17 2 25 04 MODEＲN ONCOLOGY ，Feb. 20 17 ，VOL. 25 ，NO. 04 ·6 17 · 现代肿瘤医学 年 月 第 卷第 期 女性下生殖道HPV 感染与宫颈上皮内瘤变及宫颈癌关系的病理研究 1 2 ， 白焕焕 蔡江义 Ｒelation of female lower genital tract HPV infection and cervical intraepithelial neoplasia and cervical cancer Bai Huanhuan1 ，Cai Jiangyi2 1 Dep artment of Pathology ，the First Hosp ital of Traditional Chinese Medicine of Yulin City ，Shaanxi Yulin 7 19000 ，China ; 2 Dep artment of Pathology ，the First X i＇an A erosp ace General Hosp ital ，Shaanxi X i＇an 7 10 100 ，China． 【Abstract 】 Obj ective : To investigate the relationship between genital HPV infection and cervical intraepithelial ne- oplasia and cervical cancer in women ． Methods : All 236 cases of CIN and cervical cancer patients were selected as observation group ，with lower genital tract HPV ( human papilloma virus) detection ，126 cervicitis patients were con- trols． Ｒesults : HＲ － HPV infection in patients with the severity of CIN increased ，HＲ － HPV infection of cervical cancer was 9 1． 89 % ( P ＜ 0 ． 05 ) ． HＲ － HPV infection and double infection rates of multiple HＲ － HPV infection in patients with a single HＲ － HPV was higher ( P ＜ 0 ． 05 ) ． Conclusion : HＲ － HPV infection and multiple HＲ － HPV infection is a major cause of cervical intraepithelial neoplasia and cervical cancer ． 【Key words 】female lower genital tract ，HPV infection ，cervical intraepithelial neoplasia ，cervical cancer ，correlation Modern Oncology 20 17 ，25 ( 04 ) : 06 17 － 06 19 【 】 : (high risk human papillomavirus ，HＲ － HPV ) 摘要 目的 探讨女性下生殖道高危型人乳头状瘤病毒