氯吡格雷联合阿司匹林在急性轻度脑梗死治疗中应用.doc

氯吡格雷联合阿司匹林在急性轻度脑梗死治疗中应用 　　【摘要】 目的 探究氯吡格雷联合阿司匹林在急性轻度脑梗死治疗中的临床治疗效果。方法 84例 急性轻度脑梗死患者， 以患者的病情为根据将患者分为对照组（38例）和实验组（46例）。对照组患者采用阿司匹林治疗， 实验组患者采用氯吡格雷联合阿司匹林治疗。比较两组患者的临床治疗和不良反应发生情况。结果 治疗14 d后， 实验组患者治疗有效45例， 有效率为97.8%；对照组患者治疗有效31例， 有效率为81.6%， 实验组患者治疗有效率高于对照组， 差异具有统计学意义（P0.05）。两组患者不良反应均较轻。结论 通过联合氯吡格雷与阿司匹林对急性轻度脑梗死患者实施临床治疗， 阻止了卒中的发展， 安全系数更高， 提升了预后质量 【关键词】 氯吡格雷；阿司匹林；脑梗死；联合治疗 DOI：10.14163/j.cnki.11-5547/r.2017.09.053 Application of clopidogrel combined with aspirin in the treatment of acute mild cerebral infarction GAO Xian-guo. Juancheng County Second People’s Hospital， Heze 274600， China 【Abstract】 Objective To investigate clinical effect by clopidogrel combined with aspirin in the treatment of acute mild cerebral infarction. Methods A total of 84 patients with acute mild cerebral infarction were divided by their disease state into control group （38 cases） and experimental group （46 cases）. The control group received aspirin for treatment， and the experimental group received clopidogrel combined with aspirin for treatment. Comparison was made on clinical effect and adverse reactions between the two groups. Results After 14-d treatment， the experimental group had 45 effective cases， with effective rate as 97.8%. The control group had 31 effective cases， with effective rate as 81.6%. The experimental group had higher effective rate in treatment than the control group， and the difference had statistical significance （P0.05）. Both groups had mild adverse reactions. Conclusion Combination of clopidogrel and aspirin in clinical treatment of acute mild cerebral infarction inhibit development of stroke with high safety factor， and it improves quality of prognosis. 【Key words】 Clopidogrel； Aspirin； Cerebral infarction； Combined treatment 急性?X梗死是临床上一种常见的脑血管疾病， 发病率较高， 发病中能导致局部脑组织发生缺血缺氧甚至坏死， 患者会表现出运动、语言方面的神经功能障碍， 极易导致患者残疾或者死亡[1-3]。现代医学研究发现， 血小板的聚集率变化以及活化会导致脑梗死患者形成动脉粥样硬化血栓。因此对血小板的聚集和活化性进行有效的控制， 可以提高脑梗死患者的预后效果及神经系统功能的恢复[4]。为了进一步对此进行探究， 本文以本院84例脑梗死患者为例进行了医学探究， 相关内容报告如下 1 资